Cytochrome P450 (CYP) 1B1 is overexpressed in tumor cells and is also recognized as a
biomarker of the tumor phenotype. This review highlights the tremendous potential of this …

Abstract Cytochrome P450 CYP1B1 is a recently cloned dioxin-inducible form of the
cytochrome P450 family of xenobiotic metabolizing enzymes. An antibody raised against a …

Significance: Targeted cancer therapy with minimal off-target consequences has shown
promise for some cancer types. Although cytochrome P450 (CYP) consists of 18 families …

Cytochrome P450s (CYPs) represent a large class of heme-containing enzymes that
catalyze the metabolism of multitudes of substrates both endogenous and exogenous. Until …

The expression of drug metabolising cytochrome P450s (CYPs) notably 1A, 1B, 2C, 3A, 2D
subfamily members have been identified in a wide range of human cancers. Individual …

The cytochrome P450s are an essential group of enzymes involved in metabolism of drugs,
foreign chemicals, arachidonic acid, cholesterol, steroids and other important lipids. The …

Cytochrome P450 4B1 (CYP4B1) plays crucial roles in biotransforming of xenobiotics. Its
predominant extrahepatic expression has been associated with certain tissue-specific …

The cytochromes P450 (CYPs) are key enzymes in cancer formation and cancer treatment.
They mediate the metabolic activation of numerous precarcinogens and participate in the …

A novel human cytochrome P450, CYP2W1, was cloned and expressed heterologously. No
or very low CYP2W1 mRNA levels were detected in fetal and adult human tissues …

Cytochrome P450 CYP1B1 is a relatively recently identified member of the CYP1 gene
family. The purpose of this commentary is to review the regulatory mechanisms, metabolic …