Abstract Background Exposure to Mn results in a neurological syndrome known as
manganism. Methods We examined how 4-week Mn exposure (20 mg/kg MnCl 2 po, 5 …

The molecular mechanisms mediating manganese (Mn)‐induced neurotoxicity, particularly
in the immature central nervous system, have yet to be completely understood. In this study …

Manganese (Mn) is a naturally occurring element and an essential nutrient for humans and
animals. However, exposure to high levels of Mn may cause neurotoxic effects …

It is hypothesized that manganese neurotoxicity could be secondary to a diminuition of
cellular protective and scavenger mechanisms. Since manganese is known to be …

Manganese (Mn) is an essential trace element, but insufficient or excessive bodily amounts
can induce neurotoxicity. Mn can directly increase neuronal insulin and activate insulin-like …

Manganese (Mn) is an important trace element that functions as a cofactor for a multitude of
enzymes at physiological levels, but excessive cellular Mn accumulation can be neurotoxic …

Objective To probe the effect of sodium para-aminosalicylate (PAS-Na) on concentration of
amino acid neurotransmitters including glutamate (Glu), glutamine (Gln), glycine (Gly) and …

Manganese (Mn) is an essential trace element found in many enzymes, however, excessive
Mn-exposure can result in manganism which is similar to Parkinson's movement disorder …

Manganese (Mn) is an essential trace element, but excess exposure leads to accumulation
in biological tissues, including the brain. Chronically high Mn levels in the brain are …

Exposure to elevated levels of Manganese (Mn) can result in an irreversible brain disease
characterized by extrapyramidal signs and symptoms resembling Parkinson's disease. To …