Manganese (Mn) is a trace element essential for brain development and functioning of the
central nervous system. However, there is a lack of information concerning the neurotoxicity …

Although essential, manganese (Mn) intake in excess leads to neurotoxicity. Mn
neurotoxicity induces impairment of energy metabolism and ultimately cell death …

Excessive manganese (Mn) induces oxidative stress and dopaminergic neurodegeneration.
However, the relationship between them during Mn neurotoxicity has not been clarified. The …

Introduction Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's
disease, Huntington's disease, amyotrophic lateral sclerosis and prion disease represent …

Manganese is an important metal for human health, being absolutely necessary for
development, metabolism, and the antioxidant system. Nevertheless, excessive exposure or …

Manganese (Mn) is an essential trace element required for many physiological functions
including proper biochemical and cellular functioning of the central nervous system (CNS) …

Objectives This study tested whether sodium para-amino salicylic dihydrate, an antibacterial
drug for tuberculosis, could block manganese-induced apoptosis in SK-N-MC neurons …

Since manganese (Mn2+) is known to be sequestered in glial cells, we investigated possible
neurotoxic mechanisms involving astrocytesin vitro. Low concentrations of Mn2+ were toxic …

Subacute exposure to manganese (Mn) produced Parkinson's disease-like syndrome called
Manganism. Chronic onset and progression are characteristics of Manganism, therefore, this …

Manganese (Mn) is an essential element for biological systems; however occupational
exposure to high levels of this metal may lead to neurodegenerative disorders, resembling …