Purification, Conformational Analysis, and Properties of a Family of Tigerinin Peptides from Skin Secretions of the Crowned Bullfrog Hoplobatrachus occipitalis
CM McLaughlin, S Lampis, M Mechkarska… - Journal of natural …, 2016 - ACS Publications
Four host-defense peptides belonging to the tigerinin family (tigerinin-1O: RICTPIPFPMCY;
tigerinin-2O: RTCIPIPLVMC; tigerinin-3O: RICTAIPLPMCL; and tigerinin-4O: RTCIPIPPVCF) …
tigerinin-2O: RTCIPIPLVMC; tigerinin-3O: RICTAIPLPMCL; and tigerinin-4O: RTCIPIPPVCF) …
Insulin-releasing and cytotoxic properties of the frog skin peptide, tigerinin-1R: a structure–activity study
The frog skin host-defense peptide tigerinin-1R (RVCSAIPLPICH. NH 2) is insulinotropic
both in vitro and in vivo. This study investigates the effects on insulin release and cytotoxicity …
both in vitro and in vivo. This study investigates the effects on insulin release and cytotoxicity …
Tigerinin‐1R: a potent, non‐toxic insulin‐releasing peptide isolated from the skin of the Asian frog, Hoplobatrachus rugulosus
Aim: Characterization of peptides in the skin of the Vietnamese common lowland frog
Hoplobatrachus rugulosus with the ability to stimulate insulin release in vitro and improve …
Hoplobatrachus rugulosus with the ability to stimulate insulin release in vitro and improve …
Effects of tigerinin peptides on cytokine production by mouse peritoneal macrophages and spleen cells and by human peripheral blood mononuclear cells
The tigerinins are a family of cationic, cyclic peptides of unknown biological function
produced in the skins of diverse frog species. Tigerinin-1R (RVCSAIPLPICH. NH 2) from …
produced in the skins of diverse frog species. Tigerinin-1R (RVCSAIPLPICH. NH 2) from …
Purification, characterization and cloning of two novel tigerinin-like peptides from skin secretions of Fejervarya cancrivora
Y Song, Y Lu, L Wang, H Yang, K Zhang, R Lai - Peptides, 2009 - Elsevier
While investigating the innate defense of brackish water-living amphibian and its
comparison with freshwater-living amphibians, two novel 12-residue antimicrobial peptides …
comparison with freshwater-living amphibians, two novel 12-residue antimicrobial peptides …
Beneficial effects of tigerinin-1R on glucose homeostasis and beta cell function in mice with diet-induced obesity-diabetes
Aims This paper investigates the anti-diabetic effects of tigerinin-1R (RVCSAIPLPICH. NH
2), a previously described amphibian host defence peptide, in mice with diet-induced …
2), a previously described amphibian host defence peptide, in mice with diet-induced …
Molecular mechanisms mediating the beneficial metabolic effects of [Arg4]tigerinin-1R in mice with diet-induced obesity and insulin resistance
OO Ojo, DK Srinivasan, BO Owolabi… - Biological …, 2016 - degruyter.com
The frog skin host-defense peptide tigerinin-1R stimulates insulin release in vitro and
improves glucose tolerance and insulin sensitivity in animal models of type 2 diabetes. This …
improves glucose tolerance and insulin sensitivity in animal models of type 2 diabetes. This …
[HTML][HTML] Purification, conformational analysis and cytotoxic activities of host-defense peptides from the Tungara frog Engystomops pustulosus (Leptodactylidae; …
The amphibian family Leptodactylidae is divided into three sub-families: Leiuperinae,
Leptodactylinae, and Paratelmatobiinae. Host-defense peptides (HDPs) present in the skins …
Leptodactylinae, and Paratelmatobiinae. Host-defense peptides (HDPs) present in the skins …
[HTML][HTML] Purification, Conformational Analysis and Cytotoxic Activities of Host-Defense Peptides from the Giant Gladiator Treefrog Boana boans (Hylidae: Hylinae)
Frogs from the extensive amphibian family Hylidae are a rich source of peptides with
therapeutic potential. Peptidomic analysis of norepinephrine-stimulated skin secretions from …
therapeutic potential. Peptidomic analysis of norepinephrine-stimulated skin secretions from …
Peptides from frog skin with potential for development into agents for Type 2 diabetes therapy
Several frog skin peptides, first identified as result of their antimicrobial or
immunomodulatory activities, have subsequently been shown to stimulate insulin release …
immunomodulatory activities, have subsequently been shown to stimulate insulin release …