We enrolled 54 adults, assessed as ASA class I or II, into this double-blind, prospective
investigation to receive 40 mL of 0.5% ropivacaine or levobupivacaine with 1: 200,000 …

We have compared the efficacy of 0.25% S (-)-bupivacaine with 0.25% RS-bupivacaine in
providing epidural analgesia for labour in a randomized, multicentre, double-blind study …

The clinical efficacy and pharmacokinetics of long‐term epidural ropivacaine infusion were
investigated in 18 postoperative children aged between 0.3 and 7.3 yr. A lumbar or thoracic …

Compared with bupivacaine, both agents may be considered as 'more well tolerated'but not
as 'totally well tolerated', as they are still capable of inducing systemic and local toxicity …

Background. Ropivacaine provides effective spinal anaesthesia for total hip arthroplasty.
This study was designed to compare the efficacy and safety of plain ropivacaine with plain …

Background Ropivacaine, a new local anesthetic, is less cardiotoxic in adults and is less
likely to cause motor blockade than is bupivacaine. The authors evaluated the clinical …

The aim of this study was to evaluate the pharmacokinetics and efficacy of the new local
anesthetic ropivacaine when used for epidural infusion for up to 72 h after major orthopedic …

Local anaesthetics are responsible for 5 to 10% of all reported adverse reactions to
anaesthetic drugs. Adverse effects may be classified as:(a) those associated directly with …

We have used the technique of randomized, double-blind sequential allocation to compare
the minimum local analgesic concentrations (MLAC) of epidural bupivacaine and …

The purpose of our study was to determine the lowest concentration of ropivacaine that
offers pain relief for the initiation of labor epidural analgesia. Women in active labor were …