Background Neuromyelitis optica (NMO) is a demyelinating disease of the central nervous
system (CNS) of putative autoimmune aetiology. Early discrimination between multiple …

Background Neuromyelitis optica (NMO), a severe demyelinating disease, represents itself
with optic neuritis and longitudinally extensive transverse myelitis. Serum NMO-IgG …

Neuromyelitis optica (NMO) is a severe inflammatory CNS disorder of putative autoimmune
aetiology, which predominantly affects the spinal cord and optic nerves. Recently, a highly …

Background: Antibodies to aquaporin-4 (AQP4-Ab), known as NMO-IgG, are a sensitive and
specific marker for neuromyelitis optica (NMO). Methods: To develop an enzyme-linked …

Abstract Aquaporin‐4 (AQP 4) is a water channel protein that is most highly, but not
exclusively, expressed in the central nervous system. In 2005 AQP 4 was shown to be the …

Antibodies to aquaporin-4 (also known as AQP4-Ab or NMO-IgG) are sensitive and highly
specific serum markers of autoimmune neuromyelitis optica (NMO). Second-generation …

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that principally targets
the optic nerves and spinal cord and often leads to severe disability and occasionally life …

Objective: To optimize aquaporin-4 (AQP4) antibody (Ab) detection and to assess the
influence of the increased sensitivity of the assay on the demographic and disease-related …

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that typically affects
optic nerves and spinal cord. Its pathogenic relationship to multiple sclerosis (MS) is …

NMO-IgG is a disease-specific autoantibody for neuromyelitis optica (NMO) and its target
antigen is aquaporin-4 (AQP4) water channel. Recently, we established a sensitive anti …