Systematic review and meta-analysis of cannabis treatment for chronic pain

E Martín-Sánchez, TA Furukawa, J Taylor… - Pain …, 2009 - academic.oup.com
Setting. Cannabis preparations have been used as a remedy for thousands of years in
traditional medicine. Clinical use of cannabinoid substances is restricted, due to legal and …

[HTML][HTML] Cannabis-based medicine for neuropathic pain and spasticity—a multicenter, randomized, double-blinded, placebo-controlled trial

JS Hansen, S Gustavsen, H Roshanisefat, M Kant… - Pharmaceuticals, 2023 - mdpi.com
Patients with multiple sclerosis (MS) and spinal cord injury (SCI) commonly sustain central
neuropathic pain (NP) and spasticity. Despite a lack of consistent evidence, cannabis-based …

Cannabinergic pain medicine: a concise clinical primer and survey of randomized-controlled trial results

SK Aggarwal - The Clinical Journal of Pain, 2013 - journals.lww.com
Objectives: This article attempts to cover pragmatic clinical considerations involved in the
use of cannabinergic medicines in pain practice, including geographical and historical …

Clinical practice guidelines for cannabis and cannabinoid-based medicines in the management of chronic pain and co-occurring conditions

AD Bell, C MacCallum, S Margolese… - Cannabis and …, 2024 - liebertpub.com
Background: One in five individuals live with chronic pain globally, which often co-occurs
with sleep problems, anxiety, depression, and substance use disorders. Although these …

Oromucosal Δ9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial

DJ Rog, TJ Nurmikko, CA Young - Clinical therapeutics, 2007 - Elsevier
Background: Central neuropathic pain (CNP), pain initiated or caused by a primary lesion or
dysfunction of the central nervous system, occurs in~ 28% of patients with multiple sclerosis …

[HTML][HTML] Cannabinoids and pain: new insights from old molecules

S Vučković, D Srebro, KS Vujović, Č Vučetić… - Frontiers in …, 2018 - frontiersin.org
Cannabis has been used for medicinal purposes for thousands of years. The prohibition of
cannabis in the middle of the 20th century has arrested cannabis research. In recent years …

A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of …

RM Langford, J Mares, A Novotna, M Vachova… - Journal of …, 2013 - Springer
Central neuropathic pain (CNP) occurs in many multiple sclerosis (MS) patients. The
provision of adequate pain relief to these patients can very difficult. Here we report the first …

Pharmacological management of pain in patients with multiple sclerosis

C Solaro, MM Uccelli - Drugs, 2010 - Springer
Multiple sclerosis (MS) is an inflammatory, demyelinating, autoimmune disease of the CNS.
There are currently a number of disease-modifying medications for MS that modulate or …

The effects of cannabis, cannabinoids, and their administration routes on pain control efficacy and safety: A systematic review and network meta-analysis

K Rabgay, N Waranuch, N Chaiyakunapruk… - Journal of the American …, 2020 - Elsevier
Objectives To determine the effects of cannabis, cannabinoids, and their administration
routes on pain and adverse euphoria events. Data sources A systematic search was …

The endocannabinoid system and neuropathic pain

R Maldonado, JE Baños, D Cabañero - Pain, 2016 - journals.lww.com
The research of new therapeutic strategies for neuropathic pain represents a major current
priority. Important drawbacks to advance in the development of these therapies are the …