Background: Pharmacological management of chronic neuropathic pain (CNP) still
represents a major clinical challenge. Collective harnessing of both the scientific evidence …

Background There has been increased interest in the role of cannabis for treating medical
conditions. The availability of different cannabis-based products can make the side effects of …

Cannabis has been widely used as a medicinal agent in Eastern medicine with earliest
evidence in ancient Chinese practice dating back to 2700 BC. Over time, the use of medical …

The combination of the ongoing opioid crisis, inappropriateness of long-term use of NSAIDs,
limited efficacy and tolerability of existing analgesics and the fact that no new analgesics …

Neuropathic pain is a worldwide epidemic that occurs in 3 to 8% of individuals in
industrialized countries and is often refractory to existing treatments. Drugs currently …

Multiple sclerosis (MS) is known as an autoimmune disease that damages the neurons in
the central nervous system. MS is characterized by its most common symptoms of spasticity …

Background This review is one of a series on drugs used to treat chronic neuropathic pain.
Estimates of the population prevalence of chronic pain with neuropathic components range …

Importance Persistent pain is a common and disabling health problem that is often difficult to
treat. There is an increasing interest in medicinal cannabis for treatment of persistent pain; …

Cannabinoid compounds include phytocannabinoids, endocannabinoids, and synthetics.
The two primary phytocannabinoids are delta-9-tetrahydrocannabinol (THC) and …

The President of the International Association for the Study of Pain established a task force
on cannabis and cannabinoid analgesia to systematically examine the evidence on (1) …