The Wnt signaling pathway is implicated in a variety of biological processes ranging from
developmental cell fate to human disease. The components involved in Wnt signaling have …

The Wnt (wingless-type) signaling pathway plays an important role in embryonic
development, tissue homeostasis, and tumor progression becaluse of its effect on cell …

Secreted frizzled-related protein (SFRP) 2, an identified member of the SFRPs family of
molecules, is often methylated in human cancers and its down-regulation is closely related …

Secreted frizzled-related proteins (SFRPs), containing five family members (SFRPs 1–5) are
putative extracellular Wnt inhibitors. Given their abilities to inhibit Wnt signalling, as well as …

Secreted frizzled-related proteins (sFRPs) constitute a family of proteins, which impede the
Wnt signaling pathway. Upregulation of the Wnt cascade is one of the multiple facets of …

Secreted frizzled related protein 1 (SFRP1) is an antagonist of the transmembrane frizzled
receptor, a component of the Wnt signaling pathway, and has been suggested to be a …

Secreted frizzled‐related proteins (sFRPs) are glycoproteins that are recognized as Wnt
antagonists. To identify the functional domains that are involved in Wnt antagonist function …

Purpose Secreted frizzled related proteins (SFRPs) play important roles in tumor progress
through antagonizing Wnt signaling. However, SFRPs has not been systematically studied …

The secreted Frizzled-related proteins (SFRPs) are a family of soluble proteins that are
structurally related to Frizzled (Fz) proteins, the serpentine receptors that mediate the …

Secreted frizzled-related proteins (SFRP) are glycoproteins containing a so-called frizzled-
like cysteine-rich domain. This domain enables them to bind to Wnt ligands or frizzled (FzD) …