While research has identified an important contribution for metals, such as iron, in microbial
pathogenesis, the roles of other transition metals, such as copper, remain mostly unknown …

Cryptococcus neoformans and Cryptococcus gattii are encapsulated yeast agents of
cryptococcosis and facultative intracellular pathogens. The interaction of these yeasts with …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes serious human
disease in immunocompromised populations. Its polysaccharide capsule is a key virulence …

Cryptococcus species are fungal pathogens that are a leading cause of mortality. Initial
inoculation is through the pulmonary route and, if disseminated, results in severe invasive …

Phosphate acquisition by fungi is regulated by the phosphate-sensing and acquisition
(PHO) signaling pathway. Cryptococcus neoformans disseminates from the lung to the brain …

The production of a polysaccharide capsule is a critical virulence factor for the AIDS-
associated fungal pathogen Cryptococcus neoformans. Capsule formation is responsive to a …

Cryptococcus neoformans causes life-threatening meningoencephalitis in humans, but its
overall biological and pathogenic regulatory circuits remain elusive, particularly due to the …

Cryptococcus neoformans is an encapsulated fungal pathogen that primarily infects the
central nervous system of immunocompromised individuals, causing life-threatening …

Cryptococcus neoformans and Cryptococcus gattii are the cause of life-threatening
meningoencephalitis in immunocompromised and immunocompetent individuals …

Passage in mice of opportunistic pathogens such as Cryptococcus neoformans is known to
increase virulence, but little is known about the molecular mechanisms involved in virulence …