[HTML][HTML] Exosomes as mediators of intercellular crosstalk in metabolism

R Isaac, FCG Reis, W Ying, JM Olefsky - Cell metabolism, 2021 - cell.com
Exosomes are nanoparticles secreted by all cell types and are a large component of the
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …

[HTML][HTML] The machinery of exosomes: biogenesis, release, and uptake

SV Krylova, D Feng - International Journal of Molecular Sciences, 2023 - mdpi.com
Exosomes are a subtype of membrane-contained vesicles 40–200 nm in diameter that are
secreted by cells into their surroundings. By transporting proteins, lipids, mRNA, miRNA …

Exosomes as new players in metabolic organ cross‐talk

C Guay, R Regazzi - Diabetes, Obesity and Metabolism, 2017 - Wiley Online Library
Blood glucose homeostasis requires a constant communication between insulin‐secreting
and insulin‐sensitive cells. A wide variety of circulating factors, including hormones …

Exosomes: Therapy delivery tools and biomarkers of diseases

L Barile, G Vassalli - Pharmacology & therapeutics, 2017 - Elsevier
Virtually all cells in the organism secrete extracellular vesicles (EVs), a heterogeneous
population of lipid bilayer membrane-enclosed vesicles that transport and deliver payloads …

Exosomes: novel biomarkers for clinical diagnosis

J Lin, J Li, B Huang, J Liu, X Chen… - The scientific world …, 2015 - Wiley Online Library
Exosomes are 30–120 nm endocytic membrane‐derived vesicles that participate in cell‐to‐
cell communication and protein and RNA delivery. Exosomes harbor a variety of proteins …

Exosomes in liver pathology

K Sato, F Meng, S Glaser, G Alpini - Journal of hepatology, 2016 - Elsevier
Exosomes are small (∼ 100 nm) membrane-bound extracellular vesicles released by
various types of cells into biological fluids. They contain proteins, mRNAs and miRNAs as …

[HTML][HTML] Signaling pathways in exosomes biogenesis, secretion and fate

L Urbanelli, A Magini, S Buratta, A Brozzi, K Sagini… - Genes, 2013 - mdpi.com
Exosomes are small extracellular vesicles (30–100 nm) derived from the endosomal system,
which have raised considerable interest in the last decade. Several studies have shown that …

Exosomes: new players in cell–cell communication

C Bang, T Thum - The international journal of biochemistry & cell biology, 2012 - Elsevier
Exosomes are small membrane vesicles of endosomal origin, which are secreted from a
variety of cell types. During the 1980s exosomes were first described as organelles to …

[HTML][HTML] Role of adipose tissue derived exosomes in metabolic disease

RY Mei, WW Qin, YH Zheng, Z Wan… - Frontiers in Endocrinology, 2022 - frontiersin.org
Adipose tissues perform physiological functions such as energy storage and endocrine,
whose dysfunction will lead to severe metabolic disorders. Accumulating evidences show …

The multifaceted exosome: biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities

S Pant, H Hilton, ME Burczynski - Biochemical pharmacology, 2012 - Elsevier
Exosomes are bioactive vesicles derived from the cell's endosomal membrane system and
secreted into surrounding body fluids. Exosomes contain cell and cell-state specific cargos …