Genetic engineering of filamentous fungi—progress, obstacles and future trends

V Meyer - Biotechnology advances, 2008 - Elsevier
Filamentous fungi are widely used in biotechnology as cell factories for the production of
chemicals, pharmaceuticals and enzymes. In order to improve their productivities, genetic …

Nonribosomal peptides in fungal cell factories: from genome mining to optimized heterologous production

A Vassaux, L Meunier, M Vandenbol, D Baurain… - Biotechnology …, 2019 - Elsevier
Fungi are notoriously prolific producers of secondary metabolites including nonribosomal
peptides (NRPs). The structural complexity of NRPs grants them interesting activities such …

Strategies and challenges for the development of industrial enzymes using fungal cell factories

J Arnau, D Yaver, CM Hjort - Grand challenges in fungal biotechnology, 2020 - Springer
Industrial enzymes have been produced from microorganisms for more than a century.
Today, a large share of enzyme products is manufactured using recombinant …

Stable production of recombinant proteins in filamentous fungi-problems and improvements

MG Wiebe - Mycologist, 2003 - cambridge.org
Filamentous fungi such as Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei
are able to produce and secrete large concentrations of enzymes (eg amylases, proteases …

[图书][B] Biotechnology of filamentous fungi: technology and products

DB Finkelstein - 2013 - books.google.com
Biotechnology of Filamentous Fungi: Technology and Products provides a comprehensive
discussion of the molecular biology, genetics, and biochemistry of filamentous fungi. It also …

[HTML][HTML] Fungal biotechnology: From yesterday to tomorrow

MG Roth, NM Westrick, TT Baldwin - Frontiers in Fungal Biology, 2023 - frontiersin.org
Fungi have been used to better the lives of everyday people and unravel the mysteries of
higher eukaryotic organisms for decades. However, comparing progress and development …

Fungal biodiversity to biotechnology

FS Chambergo, EY Valencia - Applied microbiology and biotechnology, 2016 - Springer
Fungal habitats include soil, water, and extreme environments. With around 100,000 fungus
species already described, it is estimated that 5.1 million fungus species exist on our planet …

[HTML][HTML] Genetic engineering of filamentous fungi for efficient protein expression and secretion

Q Wang, C Zhong, H Xiao - Frontiers in Bioengineering and …, 2020 - frontiersin.org
Filamentous fungi are considered as unique cell factories for protein production due to the
high efficiency of protein secretion and superior capability of post-translational modifications …

Heterologous protein expression in filamentous fungi

KMH Nevalainen, VSJ Te'o, PL Bergquist - Trends in biotechnology, 2005 - cell.com
Filamentous fungi are commonly used in the fermentation industry for the large-scale
production of proteins–mainly industrial enzymes. Recent advances in fungal genomics and …

Future insights in fungal metabolic engineering

S Wakai, T Arazoe, C Ogino, A Kondo - Bioresource technology, 2017 - Elsevier
Filamentous fungi exhibit versatile abilities, including organic acid fermentation, protein
production, and secondary metabolism, amongst others, and thus have applications in the …