In the Swiss Ketanserin Study the antihypertensive efficacy and tolerability of ketanserin
(given in 20 or 40 mg doses twice daily) was investigated, after a placebo run-in phase, as …

The effects of chronic oral treatment with the 5-hydroxytryptamine (serotonin) receptor
blocking agent ketanserin (17 mg/100 g dry food) on blood pressure, heart weight …

Ketanserin, an investigational, antiserotonergic agent, at a dose of 40 mg bid was given to
18 patients with mild to moderate primary hypertension in a randomized, double‐blind …

Abstract Ketanserin (3× 40 mg daily) was administered during 6 weeks in 14 patients with
mild to moderate essential hypertension using a double-blind, placebo-controlled, crossover …

Abstract Interactions between 5-hydroxytryptamine (5-HT) and the so-called 5-HT2 receptor
antagonists ketanserin, spiperone, trazodone and methysergide were studied in isolated …

Ketanserin, a new selective 5-HT,-serotonergic antagonist, was used to:(a) confirm its
hypotensive efficacy in acute and long-term treatment,(h) determine its influence on the …

In vitro affinity for vascular 5HT2 and alpha receptors was determined for several
compounds (spiperone, ketanserin, mianserin, trazodone, mepiprazole, benzoctamine, m …

1 Using a number of agonist and antagonist compounds, we have attempted to characterize
the responses and receptors involved in the effects of 5‐hydroxytryptamine (5‐HT) in the …

The pharmacokinetics of ketanserin (R 41468), a novel serotonin S 2-receptor blocking
agent widely investigated for its effect on acute and chronic hypertension, has been studied …

Various circulating substances are involved in blood pressure control in humans and among
these, the effects of serotonin have been well recognized. Its importance in human …