Importance of the field: Selectins play a significant and well-documented role in
inflammation and immune response. They initiate tethering and rolling of blood borne …

The selectins play a significant role in mediating cellular adhesion and thus initiating the
inflammatory and cell-mediated immune responses. In an inflammatory response, the …

A characteristic feature of an inflammatory reaction is the infiltration of leucocytes from the
vascular circulation into affected tissues. This process is initiated by the selectin …

Selectins mediate tethering and rolling of leukocytes to the vascular endothelium, the first
adhesive step in the recruitment of immune cells to inflamed tissues. Thus, selectins play a …

Introduction: Selectins mediate tethering and rolling of leukocytes to the vascular
endothelium, the first adhesive step in the recruitment of immune cells to inflamed tissues …

The selectins are a family of cell-adhesion proteins that mediate the early stages of
leukocyte recruitment from the blood stream to sites of tissue damage through recognition of …

Inhibition of selectin function is expected to aid in the management of diseases
characterized by aberrant or chronic inflammation, as in asthma and chronic obstructive …

Selectins are multifunctional adhesion molecules that mediate the initial interactions
between circulating leukocytes and cells of the endothelium. First identified over a decade …

Selectin enzymes are glycoproteins and are an important adhesion molecule in the
mammalian immune system, especially in the inflammatory response and the healing …

Selectins are carbohydrate-binding molecules that bind to fucosylated and sialylated
glycoprotein ligands, and are found on endothelial cells, leukocytes and platelets. They are …