Effects of triclosan on the RedoximiRs/Sirtuin/Nrf2/ARE signaling pathway in mosquitofish (Gambusia affinis)

S Bao, C He, P Ku, M Xie, J Lin, S Lu, X Nie - Aquatic Toxicology, 2021 - Elsevier
Triclosan (TCS) has been widely used in daily life for its broad-spectrum antibacterial
property and subsequently detected frequently in aquatic waterborne. Environmental …

Exposure to triclosan changes the expression of microRNA in male juvenile zebrafish (Danio rerio)

F Wang, F Liu, W Chen - Chemosphere, 2019 - Elsevier
Triclosan (TCS) is a broad-spectrum antibacterial agent which is widely used in various
personal care products and cosmetics. It has been found that TCS affects endocrine …

Environmentally relevant concentrations of oxytetracycline and copper increased liver lipid deposition through inducing oxidative stress and mitochondria dysfunction …

YH Xu, C Hogstrand, YC Xu, T Zhao, H Zheng… - Environmental …, 2021 - Elsevier
Oxytetracycline (OTC) and Cu are prevalent in aquatic ecosystems and their pollution are
issues of serious concern. The present working hypothesis is that the toxicity of Cu and OTC …

The toxic effect of triclosan and methyl-triclosan on biological pathways revealed by metabolomics and gene expression in zebrafish embryos

J Fu, YXR Tan, Z Gong, S Bae - Ecotoxicology and environmental safety, 2020 - Elsevier
The omnipresence of antimicrobial triclosan (TCS) and by-products in aquatic environments
is a threat to aquatic organisms. Traditionally, the adverse effects of TCS and its by-products …

Sublethal concentrations of triclosan elicited oxidative stress, DNA damage, and histological alterations in the liver and brain of adult zebrafish

E Gyimah, X Dong, W Qiu, Z Zhang, H Xu - Environmental Science and …, 2020 - Springer
Triclosan (TCS), an antimicrobial agent, has been a pollutant of increasing concern owing to
its potential health risk on humans and aquatic animals. The present study seeks to test the …

Triclosan-induced liver and brain injury in zebrafish (Danio rerio) via abnormal expression of miR-125 regulated by PKCα/Nrf2/p53 signaling pathways

C Wang, W Huang, J Lin, F Fang, X Wang, H Wang - Chemosphere, 2020 - Elsevier
Triclosan (TCS) is widely used in personal care products, and its chronic exposure leads to
severely toxic effects in zebrafish (Danio rerio). PKCα, Nrf2 and p53 are three important …

Triclosan induced zebrafish immunotoxicity by targeting miR-19a and its gene socs3b to activate IL-6/STAT3 signaling pathway

C Zhao, R Xie, Q Qian, J Yan, H Wang… - Science of the Total …, 2022 - Elsevier
As a broad-spectrum antibacterial agent, triclosan (TCS) has been confirmed to possess
potential immunotoxicity to organisms, but the underlying mechanisms remains unclear …

Effects of triclosan on antioxidant-and apoptosis-related genes expression in the gill and ovary of zebrafish

F Wang, F Zheng, F Liu - Experimental Animals, 2020 - jstage.jst.go.jp
Triclosan (TCS) is a broad-spectrum antibacterial and anti-fungal agent used in a broad
variety of personal care products (PCPs) throughout the world. However, the molecular …

Mechanism-based understanding of the potential cellular targets of triclosan in zebrafish larvae

F Wang, F Liu - Environmental Toxicology and Pharmacology, 2023 - Elsevier
Triclosan (TCS) has become widely distributed due to its widespread use. In this study, we
investigated the mechanisms of TCS's potential effects on cellular targets in zebrafish (Danio …

Tetracycline antibiotics as PI3K inhibitors in the Nrf2-mediated regulation of antioxidative stress in zebrafish larvae

X Yu, Y Wu, M Deng, Y Liu, S Wang, X He… - Chemosphere, 2019 - Elsevier
Scientific concern about veterinary antibiotics (VAs) residues in the aquatic environment has
increased in recent years. However, little is known about the underlying molecular …