Safety and effectiveness outcomes from a 14-country cohort of patients with multi-drug resistant tuberculosis treated concomitantly with bedaquiline, delamanid, and …

H Huerga, U Khan, M Bastard… - Clinical Infectious …, 2022 - academic.oup.com
Background Concomitant use of bedaquiline (Bdq) and delamanid (Dlm) for multi-
drug/rifampicin resistant tuberculosis (MDR/RR-TB) has raised concerns about a potentially …

One step forward: successful end-of-treatment outcomes of patients with drug-resistant tuberculosis who received concomitant bedaquiline and delamanid in Mumbai …

M Das, A Dalal, C Laxmeshwar, S Ravi… - Clinical Infectious …, 2021 - academic.oup.com
Background The Médecins Sans Frontières Clinic in Mumbai, India, has been providing
concomitant bedaquiline (BDQ) and delamanid (DLM) in treatment regimen for patients with …

Bedaquiline, delamanid, linezolid, and clofazimine for treatment of pre-extensively drug-resistant tuberculosis

C Padmapriyadarsini, V Vohra… - Clinical Infectious …, 2023 - academic.oup.com
Background Treatment success rates for multidrug-resistant tuberculosis (MDR-TB) remain
low globally. Availability of newer drugs has given scope to develop regimens that can be …

Impact of Prior Tuberculosis Treatment With New/Companion Drugs on Clinical Outcomes in Patients Receiving Concomitant Bedaquiline and Delamanid for …

L Mikiashvili, RR Kempker, TS Chakhaia… - Clinical Infectious …, 2024 - academic.oup.com
Background There are scarce data on the clinical outcomes of persons retreated with
new/companion anti-tuberculosis (TB) drugs for multidrug-and rifampicin-resistant …

Combined treatment of drug-resistant tuberculosis with bedaquiline and delamanid: a systematic review

E Pontali, G Sotgiu, S Tiberi, M Tadolini… - European …, 2018 - Eur Respiratory Soc
The World Health Organization (WHO) estimated that 490 000 cases of multidrug-resistant
(MDR) tuberculosis (TB)(defined as TB caused by Mycobacterium tuberculosis strains …

[HTML][HTML] Interim treatment outcomes in multidrug-resistant tuberculosis patients treated sequentially with bedaquiline and delamanid

HH Lee, KW Jo, JJ Yim, D Jeon, H Kang… - International Journal of …, 2020 - Elsevier
Objectives The objective of this study was to evaluate the efficacy and safety of the
sequential use of bedaquiline (Bdq) and delamanid (Dlm) in patients with multidrug-resistant …

[HTML][HTML] The endTB observational study protocol: treatment of MDR-TB with bedaquiline or delamanid containing regimens

U Khan, H Huerga, AJ Khan, CD Mitnick… - BMC infectious …, 2019 - Springer
Background At a time when programs were struggling to design effective regimens for the
treatment of multidrug-resistant tuberculosis (MDR-TB), the marketing authorization of …

A regimen containing bedaquiline and delamanid compared to bedaquiline in patients with drug-resistant tuberculosis

O Olayanju, A Esmail, J Limberis… - European Respiratory …, 2020 - Eur Respiratory Soc
There are limited data on combining delamanid and bedaquiline in drug-resistant
tuberculosis (DR-TB) regimens. Prospective long-term outcome data, including in HIV …

[HTML][HTML] Bedaquiline safety, efficacy, utilization and emergence of resistance following treatment of multidrug-resistant tuberculosis patients in South Africa: a …

H Pai, N Ndjeka, L Mbuagbaw, K Kaniga… - BMC infectious …, 2022 - Springer
Background This retrospective cohort study assessed benefits and risks of bedaquiline
treatment in multidrug-resistant-tuberculosis (MDR-TB) combination therapy by evaluating …

Early safety and efficacy of the combination of bedaquiline and delamanid for the treatment of patients with drug-resistant tuberculosis in Armenia, India, and South …

G Ferlazzo, E Mohr, C Laxmeshwar… - The Lancet Infectious …, 2018 - thelancet.com
Background Bedaquiline and delamanid have been approved for treatment of multidrug-
resistant (MDR) tuberculosis in the past 5 years. Because of theoretical safety concerns …