Viruses are obligate parasites of cellular hosts and therefore are constantly confronted with
the host immune system. Evasion of innate immunity mechanisms by viruses is paramount …

The complement system surveillance in the host is effective in controlling viral propagation.
Consequently, to subvert this effector mechanism, viruses have developed a series of …

Viruses require a host for replication and survival and hence are subjected to host
immunological pressures. The complement system, a crucial first response of the host …

The complement system functions as an immune surveillance system that rapidly responds
to infection. Activation of the complement system by specific recognition pathways triggers a …

Being a major first line of immune defense, the complement system keeps a constant vigil
against viruses. Its ability to recognize large panoply of viruses and virus-infected cells, and …

The complement system is a major component of the innate immune system that recognizes
invading pathogens and eliminates them by means of an array of effector mechanisms, in …

The complement system is a potent innate immune mechanism consisting of cascades of
proteins which are designed to fight against and annul intrusion of all the foreign pathogens …

The complement system is a principal bastion of innate immunity designed to combat a
myriad of existing as well as newly emerging pathogens. Since viruses are obligatory …

The complement system represents a crucial part of innate immunity. It contains a diverse
range of soluble activators, membrane-bound receptors, and regulators. Its principal function …

Regulators of complement activation (RCA) inhibit complement‐induced immune responses
on healthy host tissues. We present crystal structures of human RCA (MCP, DAF, and CR 1) …