Correction of the anion gap for albumin in order to detect occult tissue anions in shock

M Hatherill, Z Waggie, L Purves, L Reynolds… - Archives of disease in …, 2002 - adc.bmj.com
Background: It is believed that hypoalbuminaemia confounds interpretation of the anion gap
(AG) unless corrected for serum albumin in critically ill children with shock. Aim: To compare …

Hypoalbuminaemia in critically ill children: incidence, prognosis, and influence on the anion gap

A Durward, A Mayer, S Skellett, D Taylor… - Archives of Disease in …, 2003 - adc.bmj.com
Aims: Hypoalbuminaemia has significance in adult critical illness as an independent
predictor of mortality. In addition, the anion gap is predominantly due to the negative charge …

Serum anion gap at admission as a predictor of mortality in the pediatric intensive care unit

MJ Kim, YH Kim, IS Sol, SY Kim, JD Kim, HY Kim… - Scientific reports, 2017 - nature.com
An accurate method to predict the mortality in the intensive care unit (ICU) patients has been
required, especially in children. The aim of this study is to evaluate the value of serum anion …

Anion gap, anion gap corrected for albumin, base deficit and unmeasured anions in critically ill patients: implications on the assessment of metabolic acidosis and the …

LS Chawla, S Shih, D Davison, C Junker… - BMC emergency …, 2008 - Springer
Background Base deficit (BD), anion gap (AG), and albumin corrected anion gap (ACAG)
are used by clinicians to assess the presence or absence of hyperlactatemia (HL). We set …

Correcting the anion gap for hypoalbuminaemia does not improve detection of hyperlactataemia

CH Dinh, R Ng, A Grandinetti, A Joffe… - Emergency medicine …, 2006 - emj.bmj.com
Background: An elevated lactate level reflects impaired tissue oxygenation and is a predictor
of mortality. Studies have shown that the anion gap is inadequate as a screen for …

Estimating unmeasured anions in critically ill patients: Anion‐gap, base‐deficit, and strong‐ion‐gap

DA Story, S Poustie, R Bellomo - Anaesthesia, 2002 - Wiley Online Library
We used 100 routine blood samples from critically ill patients to establish whether correcting
the anion‐gap and base‐deficit for decreased plasma albumin improves agreement with the …

Hypoalbuminemia in critically ill children

IN Horowitz, K Tai - Archives of pediatrics & adolescent medicine, 2007 - jamanetwork.com
Objective To evaluate whether hypoalbuminemia on admission is a predictor of adverse
outcome in critically ill children. Design Retrospective medical record review. Setting A 14 …

Closing the gap on unmeasured anions

JA Kellum - Critical Care, 2003 - Springer
Many critically ill and injured patients, especially those with metabolic acidosis, have
abnormally high levels of unmeasured anions in their blood. At the same time, such patients …

Electrolytes in sick neonates–which sodium is the right answer?

RI King, RJ Mackay, CM Florkowski… - Archives of Disease in …, 2013 - fn.bmj.com
Introduction Hypoproteinaemia leads to spuriously high-sodium values when measured by
indirect ion-selective electrodes (ISE) as used in main laboratory analysers compared with …

Albumin bolus administration versus continuous infusion in critically ill hypoalbuminemic pediatric patients

A Greissman, P Silver, L Nimkoff, M Sagy - Intensive care medicine, 1996 - Springer
Objective To test the hypothesis that the rate of degradation of exogenously administered
albumin is fater with bolus administration that with continuous infusion and thus that a bolus …