Various bioactivity and relationship of structure–activity of matrine analogues

W Ni, C Li, Y Liu, H Song, L Wang… - Journal of Agricultural …, 2017 - ACS Publications
For the first time, the botanic source natural product matrine was reported to have more
potent inhibitory activity against tobacco mosaic virus (TMV) than the commercial virucide …

Semi‐synthesis and characterization of some new matrine derivatives as insecticidal agents

X Cheng, H He, WX Wang, F Dong… - Pest Management …, 2020 - Wiley Online Library
BACKGROUND Matrine is an important traditional plant‐derived insecticide with broad‐
spectrum activity. However, due to its moderate activity, matrine is mainly applied in …

[HTML][HTML] Synthesis, characterization and in vitro biological evaluation of two matrine derivatives

X Cheng, J Ye, H He, Z Liu, C Xu, B Wu, X Xiong… - Scientific Reports, 2018 - nature.com
Matrine is a traditional Chinese medicine and botanical pesticide with broad biological
activities, including pharmacological and agricultural activities. In present work, two matrine …

Evaluation of biological activities, and exploration on mechanism of action of matrine–cholesterol derivatives

J Xu, Z Sun, M Hao, M Lv, H Xu - Bioorganic Chemistry, 2020 - Elsevier
To develop new potential pesticides, a series of matrine–cholesterol derivatives were
prepared by modifications of two non-food bioactive products matrine and cholesterol. Two …

Semisynthesis of Matrinic Acid/Alcohol/Ester Derivatives, Their Pesticidal Activities, and Investigation of Mechanisms of Action against Tetranychus cinnabarinus

B Zhang, Z Sun, M Lv, H Xu - Journal of Agricultural and Food …, 2018 - ACS Publications
To discover new natural-product-based potential pesticides, 85 matrinic acid/alcohol/ester
derivatives were synthesized by structural modifications of a quinolizidine alkaloid matrine …

Preparation of Matrinic/Oxymatrinic Amide Derivatives as Insecticidal/Acaricidal Agents and Study on the Mechanisms of Action against Tetranychus cinnabarinus

H Xu, M Xu, Z Sun, S Li - Journal of agricultural and food chemistry, 2019 - ACS Publications
In continuation of our program to develop natural-product-based pesticidal candidates,
matrinic/oxymatrinic amides were obtained through structural optimization of matrine. N′-(4 …

[HTML][HTML] Synthesis of halopyrazole matrine derivatives and their insecticidal and fungicidal activities

X Cheng, H He, F Dong, CC Xu, H Zhang, Z Liu, X Lv… - Molecules, 2022 - mdpi.com
Matrine is a traditional botanical pesticide with a broad-spectrum biological activity that is
widely applied in agriculture. Halopyrazole groups are successfully introduced to the C13 of …

[HTML][HTML] Design, synthesis and various bioactivity of acylhydrazone-containing matrine analogues

W Ni, H Song, L Wang, Y Liu, Q Wang - Molecules, 2023 - mdpi.com
Compounds with acylhydrazone fragments contain amide and imine groups that can act as
electron donors and acceptors, so they are easier to bind to biological targets and thus …

Agrochemical properties evaluation of some imines alkaloids of matrine/oxymatrine

M Lv, Q Ma, S Zhang, H Xu - Bioorganic & Medicinal Chemistry Letters, 2021 - Elsevier
To discover non-food renewable forest bioactive products as new potential pesticidal
alternatives for crop protection, a series of C15-imines alkaloids were obtained by structural …

[HTML][HTML] Novel Matrine Derivatives as Potential Larvicidal Agents against Aedes albopictus: Synthesis, Biological Evaluation, and Mechanistic Analysis

S Ang, J Liang, W Zheng, Z Zhang, J Li, Z Yan… - Molecules, 2023 - mdpi.com
A large number of studies have shown that matrine (MA) possesses various
pharmacological activities and is one of the few natural, plant-derived pesticides with the …