[HTML][HTML] Pleiotropic function of Toll-like receptors

T Kaisho, S Akira - Microbes and Infection, 2004 - Elsevier
A group of type I transmembrane proteins, Toll-like receptors (TLRs) discriminate various
microorganism-associated molecular structures that can function as immune adjuvants …

A noncognate interaction with anti‐receptor antibody‐activated helper T cells induces small resting murine B cells to proliferate and to secrete antibody

T Owens - European journal of immunology, 1988 - Wiley Online Library
Culture of small resting allogeneic B cells (of an irrelevant haplotype) with two clones of T
helper (Th) cells that were activated by the F23. 1 anti‐T cell receptor antibody led to the …

Ia-mediated signal transduction leads to proliferation of primed B lymphocytes.

JC Cambier, KR Lehmann - The Journal of experimental medicine, 1989 - rupress.org
One of the most controversial questions in immunology is the molecular basis by which Th
lymphocytes deliver activating signals to quiescent B lymphocytes during T cell-dependent …

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

A Ozinsky, DM Underhill, JD Fontenot… - Proceedings of the …, 2000 - National Acad Sciences
Toll-like receptors (TLRs) have been shown to participate in the recognition of pathogens by
the innate immune system, but it is not clear how a restricted family of receptors has the …

Stimulation of B-cell proliferation by membrane-associated molecules from activated T cells.

AA Brian - Proceedings of the National Academy of …, 1988 - National Acad Sciences
Activation of B cells to proliferation and antibody secretion is dependent on soluble
lymphokines secreted by activated T cells. Activation of T cells results from physical contact …

Signaling in B cells via Toll-like receptors

SL Peng - Current opinion in immunology, 2005 - Elsevier
Toll-like receptors (TLRs) and their ligands have emerged as important regulators of
immunity, relevant to a wide range of effector responses from vaccination to autoimmunity …

Characterization of the physical interaction between antigen-specific B and T cells.

VM Sanders, JM Snyder, JW Uhr… - Journal of immunology …, 1986 - journals.aai.org
It has been assumed that physical interaction between B cells and helper T cells in the
presence of specific antigen is an early and essential step in the physiologic antibody …

Regulation of T helper cell cytokine expression: functional dichotomy of antigen‐presenting cells

J Schmitz, M Assenmacher… - European journal of …, 1993 - Wiley Online Library
A bias to either cell‐mediated or antibody‐mediated effector mechanisms is induced in an
immune response against a pathogen, if activated T helper cells (Th) predominantly express …

[HTML][HTML] T cell responses to bacterial infection

KM Kerksiek, EG Pamer - Current opinion in immunology, 1999 - Elsevier
Many exciting advances in our understanding of T cell mediated immunity to bacterial
infection have occurred in the past several years. T cell responses have been more fully …

Transmembrane activator, calcium modulator, and cyclophilin ligand interactor drives plasma cell differentiation in LPS-activated B cells

E Ozcan, L Garibyan, JJY Lee, RJ Bram, KP Lam… - Journal of Allergy and …, 2009 - Elsevier
BACKGROUND: Transmembrane activator, calcium modulator, and cyclophilin ligand
interactor (TACI) expression on B cells is upregulated by Toll-like receptor (TLR) 4 …