In recent years, the pharmaceutical sector has been viewed as one of the most revenue-
generating fields which primarily deals with all the activities ranging from approving …

The Biopharmaceutics Classification System (BCS) is the scientific basis for classifying
drugs based on their aqueous solubility and intestinal permeability that supports in vivo …

Among the absorption, distribution, metabolism, elimination, and toxicity properties
(ADMET), unfavorable oral bioavailability is indeed an important reason for stopping further …

The vast majority of marketed drugs are orally administrated. As such, drug absorption is
one of the important drug metabolism and pharmacokinetics parameters that should be …

In the early 1990s, a collaborative research effort between academia and the US Food and
Drug Administration (FDA) was initiated to establish a database of human jejunal …

The absorption of a drug compound through the human intestinal cell lining is an important
property for potential drug candidates. Measuring this property, however, can be costly and …

The ability to predict the extent of passive intestinal drug absorption is very important for
efficient lead candidate selection and development. Physicochemical-based absorption …

A data set consisting of 1040 drug candidates was divided into a training set and test set of
832 and 208 compounds, respectively. The training set was used for estimating a model for …

Abstract The Biopharmaceutics Classification System is a drug development tool that
estimates the contributions of solubility, dissolution, and intestinal permeability affecting drug …