Clinical significance of extended-spectrum β-lactamases

J Rodríguez-Baño, A Pascual - Expert review of anti-infective …, 2008 - Taylor & Francis
The spread of extended-spectrum β-lactamases (ESBLs) in nosocomial and community-
acquired enterobacteria is an important challenge for clinicians as the therapeutic options …

Beta-lactam/beta-lactamase inhibitors versus carbapenem for bloodstream infections due to extended-spectrum beta-lactamase-producing Enterobacteriaceae …

MM Sfeir, G Askin, P Christos - International journal of antimicrobial agents, 2018 - Elsevier
Background Infections due to extended-spectrum beta-lactamase (ESBL)-producing
Enterobacteriaceae pose a major public health threat due to poor outcomes and high …

Carbapenems and alternative β-lactams for the treatment of infections due to extended-spectrum β-lactamase-producing Enterobacteriaceae: what impact on …

PL Woerther, R Lepeule, C Burdet… - International journal of …, 2018 - Elsevier
The ongoing pandemic of extended-spectrum β-lactamase-producing Enterobacteriaceae
(ESBL-E) is responsible for a global rise in carbapenem consumption that may hasten the …

Addressing the challenge of extended-spectrum beta-lactamases.

JR Zahar, O Lortholary, C Martin, G Potel… - Current Opinion in …, 2009 - europepmc.org
During the last decade, community-acquired extended-spectrum beta-lactamase (ESBL)-
producing bacteria, and in particular Escherichia coli producing ESBLs of the CTX-M-type …

Infections with extended-spectrum β-lactamase-producing Enterobacteriaceae: changing epidemiology and drug treatment choices

JDD Pitout - Drugs, 2010 - Springer
Since 2000, Escherichia coli producing CTX-M enzymes (especially CTX-M-15) have
emerged worldwide as important causes of community-onset urinary tract infections (UTIs) …

Extended spectrum β-lactamase (ESBL)-producing Enterobacteriaceae: considerations for diagnosis, prevention and drug treatment

ME Rupp, PD Fey - Drugs, 2003 - Springer
Extended spectrum β-lactamase (ESBL)-producing organisms pose unique challenges to
clinical microbiologists, clinicians, infection control professionals and antibacterial-discovery …

Trends in production of extended-spectrum β-lactamases among enterobacteria of medical interest: report of the second Italian nationwide survey

F Luzzaro, M Mezzatesta, C Mugnaioli… - Journal of clinical …, 2006 - Am Soc Microbiol
Results of a 2003 survey carried out in Italy to evaluate the prevalence of extended-
spectrum β-lactamase (ESBL)-producing enterobacteria are presented. Eleven Italian …

Effectiveness of third-generation cephalosporins or piperacillin compared with cefepime or carbapenems for severe infections caused by wild-type AmpC β-lactamase …

A Maillard, T Delory, J Bernier, A Villa, K Chaibi… - International Journal of …, 2023 - Elsevier
Background The optimal treatment regimen for infections caused by wild-type AmpC β-
lactamase-producing Enterobacterales remains controversial. This study compared the …

Carbapenems versus piperacillin-tazobactam for bloodstream infections of nonurinary source caused by extended-spectrum beta-lactamase–producing …

H Ofer-Friedman, C Shefler, S Sharma… - infection control & …, 2015 - cambridge.org
A recent, frequently quoted study has suggested that for bloodstream infections (BSIs) due to
extended-spectrum β-lactamase–producing Enterobacteriaceae (ESBL) Escherichia coli …

Diagnosis and treatment of extended-spectrum and AmpC β-lactamase–producing organisms

K Yang, BJ Guglielmo - Annals of Pharmacotherapy, 2007 - journals.sagepub.com
Objective: To review the laboratory diagnosis of extended-spectrum β-lactamase (ESBL)
and AmpC β-lactamase–producing bacteria and evaluate potential treatment options. Data …