[HTML][HTML] Antibody binding reports spatial heterogeneities in cell membrane organization

DP Arnold, Y Xu, SC Takatori - Nature communications, 2023 - nature.com
The spatial organization of cell membrane glycoproteins and glycolipids is critical for
mediating the binding of ligands, receptors, and macromolecules on the plasma membrane …

Engineered molecular sensors for quantifying cell surface crowding

SC Takatori, S Son, DSW Lee… - Proceedings of the …, 2023 - National Acad Sciences
Cells mediate interactions with the extracellular environment through a crowded assembly of
transmembrane proteins, glycoproteins and glycolipids on their plasma membrane. The …

[HTML][HTML] Effects of protein crowding on membrane systems

G Guigas, M Weiss - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2016 - Elsevier
Cellular membranes are typically decorated with a plethora of embedded and adsorbed
macromolecules, eg proteins, that participate in numerous vital processes. With typical …

[HTML][HTML] One, two or three? Probing the stoichiometry of membrane proteins by single-molecule localization microscopy

F Fricke, J Beaudouin, R Eils, M Heilemann - Scientific reports, 2015 - nature.com
Probing the oligomeric state of abundant molecules, such as membrane proteins in intact
cells, is essential, but has not been straightforward. We address this challenge with a simple …

Macromolecular crowding at membrane interfaces: adsorption and alignment of membrane peptides

C Aisenbrey, B Bechinger, G Gröbner - Journal of molecular biology, 2008 - Elsevier
Association of proteins to cellular membranes is involved in various biological processes.
Various theoretical models have been developed to describe this adsorption mechanism …

Size-dependent protein segregation at membrane interfaces

EM Schmid, MH Bakalar, K Choudhuri, J Weichsel… - Nature physics, 2016 - nature.com
Membrane interfaces formed at cell–cell junctions are associated with characteristic patterns
of membrane proteins whose organization is critical for intracellular signalling. To isolate the …

Intercellular receptor–ligand binding and thermal fluctuations facilitate receptor aggregation in adhering membranes

L Li, J Hu, B Różycki, F Song - Nano letters, 2019 - ACS Publications
Nanoscale molecular clusters in cell membranes can serve as platforms to recruit
membrane proteins for various biological functions. A central question is how these …

Coupled membrane fluctuations and protein mobility in supported intermembrane junctions

R Parthasarathy, JT Groves - The Journal of Physical Chemistry B, 2006 - ACS Publications
Junctions between lipid membranes make possible cell-free explorations of physical
mechanisms that can contribute to protein and lipid organization at a variety of biophysical …

Cluster formation of transmembrane proteins due to hydrophobic mismatching

U Schmidt, G Guigas, M Weiss - Physical review letters, 2008 - APS
Membranes are the defining envelopes of living cells. At this boundary a multitude of
transmembrane proteins mediate signal and mass transfer between cells and their …

Live-cell monitoring of protein localization to membrane rafts using protein-fragment complementation

M Merezhko, E Pakarinen, RL Uronen… - Bioscience …, 2020 - portlandpress.com
The plasma membrane consists of a variety of discrete domains differing from the
surrounding membrane in composition and properties. Selective partitioning of protein to …