Biological functions of lymphatic vessels

TV Petrova, GY Koh - Science, 2020 - science.org
BACKGROUND Blood and lymphatic vessel networks form two arms of the vertebrate
cardiovascular system that play complementary roles in body homeostasis maintenance and …

Low lymphocyte count and cardiovascular diseases

J Núñez, G Miñana, V Bodí, E Núñez… - Current medicinal …, 2011 - ingentaconnect.com
Inflammation plays a crucial pathophysiological role in the entire continuum of the
atherosclerotic process, from its initiation, progression, and plaque destabilization leading …

[PDF][PDF] The lymphatic vasculature in the 21st century: novel functional roles in homeostasis and disease

G Oliver, J Kipnis, GJ Randolph, NL Harvey - Cell, 2020 - cell.com
Mammals have two specialized vascular circulatory systems: the blood vasculature and the
lymphatic vasculature. The lymphatic vasculature is a unidirectional conduit that returns …

Artery tertiary lymphoid organs contribute to innate and adaptive immune responses in advanced mouse atherosclerosis

SK Mohanta, C Yin, L Peng, P Srikakulapu… - Circulation …, 2014 - Am Heart Assoc
Tertiary lymphoid organs emerge in tissues in response to nonresolving inflammation.
Recent research characterized artery tertiary lymphoid organs in the aorta adventitia of aged …

The lymphatic vasculature revisited

D Kerjaschki - The Journal of clinical investigation, 2014 - Am Soc Clin Investig
Lymphatic vessels constitute a ubiquitous countercurrent system to the blood vasculature
that returns interstitial fluid, salts, small molecules, resorbed fat, and cells to the bloodstream …

Vegfc/d-dependent regulation of the lymphatic vasculature during cardiac regeneration is influenced by injury context

CJ Vivien, C Pichol-Thievend, CB Sim… - Npj Regenerative …, 2019 - nature.com
The lymphatic vasculature mediates essential physiological functions including fluid
homeostasis, lipid and hormone transport, and immune cell trafficking. Recent studies have …

[HTML][HTML] Myocardial B cells are a subset of circulating lymphocytes with delayed transit through the heart

L Adamo, C Rocha-Resende, CY Lin, S Evans… - JCI insight, 2020 - ncbi.nlm.nih.gov
Current models of B lymphocyte biology posit that B cells continuously recirculate between
lymphoid organs, without accumulating in peripheral healthy tissues. Nevertheless, B …

Lymphoangiocrine signals promote cardiac growth and repair

X Liu, E De la Cruz, X Gu, L Balint, M Oxendine-Burns… - Nature, 2020 - nature.com
Recent studies have suggested that lymphatics help to restore heart function after cardiac
injury,,,,–. Here we report that lymphatics promote cardiac growth, repair and …

Activated T lymphocytes are essential drivers of pathological remodeling in ischemic heart failure

SS Bansal, MA Ismahil, M Goel, B Patel… - Circulation: Heart …, 2017 - Am Heart Assoc
Background—Inappropriately sustained inflammation is a hallmark of chronic ischemic heart
failure (HF); however, the pathophysiological role of T lymphocytes is unclear. Methods and …

Lymphangiogenesis in myocardial remodelling after infarction

Y Ishikawa, Y Akishima‐Fukasawa, K Ito… - …, 2007 - Wiley Online Library
Aims: The lymphatic system is involved in fluid homeostasis of the cardiac interstitium, but
lymphangiogenesis in myocardial remodelling has not previously been examined …