[HTML][HTML] Iron deficiency in heart failure: mechanisms and pathophysiology

RIS Alnuwaysir, MF Hoes, DJ van Veldhuisen… - Journal of clinical …, 2021 - mdpi.com
Iron is an essential micronutrient for a myriad of physiological processes in the body beyond
erythropoiesis. Iron deficiency (ID) is a common comorbidity in patients with heart failure …

Iron deficiency in heart failure: an overview

S von Haehling, N Ebner, R Evertz, P Ponikowski… - JACC: Heart Failure, 2019 - jacc.org
Iron deficiency is an extremely common comorbidity in patients with heart failure, affecting
up to 50% of all ambulatory patients. It is associated with reduced exercise capacity and …

Iron deficiency: an emerging therapeutic target in heart failure

A Cohen-Solal, C Leclercq, G Deray, S Lasocki… - Heart, 2014 - heart.bmj.com
In patients with heart failure, iron deficiency is frequent but overlooked, with a prevalence of
30%–50%. Since it contributes to cardiac and peripheral muscle dysfunction, iron deficiency …

Iron deficiency in heart failure

G Loncar, D Obradovic, H Thiele… - ESC heart …, 2021 - Wiley Online Library
Iron deficiency is a major heart failure co‐morbidity present in about 50% of patients with
stable heart failure irrespective of the left ventricular function. Along with compromise of daily …

The burden of iron deficiency in heart failure: therapeutic approach

BML Rocha, GJL Cunha, LF Menezes Falcao - Journal of the American …, 2018 - jacc.org
Heart failure (HF) is highlighted by its burdening symptom-limited exercise capacity and
recurrent hospitalizations. Despite substantial advances regarding disease-modifying drugs …

[HTML][HTML] Iron deficiency: a new target for patients with heart failure

C Rizzo, R Carbonara, R Ruggieri… - Frontiers in …, 2021 - frontiersin.org
Iron deficiency (ID) is one of the most frequent comorbidities in patients with heart failure
(HF). ID is estimated to be present in up to 50% of outpatients and is a strong independent …

Iron deficiency and heart failure: diagnostic dilemmas and therapeutic perspectives

EA Jankowska, S von Haehling, SD Anker… - European heart …, 2013 - academic.oup.com
Iron is a micronutrient essential for cellular energy and metabolism, necessary for
maintaining body homoeostasis. Iron deficiency is an important co-morbidity in patients with …

[HTML][HTML] Role of iron metabolism in heart failure: From iron deficiency to iron overload

H Zhang, P Zhabyeyev, S Wang, GY Oudit - Biochimica et Biophysica Acta …, 2019 - Elsevier
Iron metabolism is a balancing act, and biological systems have evolved exquisite
regulatory mechanisms to maintain iron homeostasis. Iron metabolism disorders are …

Iron deficiency: an ominous sign in patients with systolic chronic heart failure

EA Jankowska, P Rozentryt, A Witkowska… - European heart …, 2010 - academic.oup.com
Aims Beyond erythropoiesis, iron is involved in numerous biological processes crucial for
maintenance of homeostasis. Patients with chronic heart failure (CHF) are prone to develop …

Anemia and iron deficiency in heart failure: mechanisms and therapeutic approaches

DJ Van Veldhuisen, SD Anker, P Ponikowski… - Nature Reviews …, 2011 - nature.com
Anemia and iron deficiency are common in patients with heart failure (HF), and are
associated with worse symptoms and adverse outcomes in this population. Although the two …