The delivery of nasal drugs specifically to the middle meatus is of critical importance in the
medical treatment of rhinosinusitis. In this respect, topical nasal drug administration by drops …

Introduction The characterisation of nasal formulations is a critical point. However, there are
still no recommendations or guidelines in terms of standard approaches for evaluating the …

PURPOSE: To quantify the amount of aerosol deposited in different parts of the airways with
a commercially available nasal sonic jet nebulizer (NJN) using a sound effect, and to …

Background Local anaesthetics and vasoconstrictors are essential for pain control and to aid
intra‐operative haemostasis in nasal procedures. They also improve access, and reduce …

Bespak, a division of Consort Medical plc, and Queen's University Belfast have developed a
viable and unique in-vitro testing capability for nasal drug delivery devices. The aim was to …

Nasal delivery devices are not only limited to local medical therapy. The nasal route is an
alternative to invasive or oral drug administration. The penetration of bioactive molecules …

Background: Previous studies showed nasal spray in vitro tests cannot predict in vivo
deposition, pharmacokinetics, or pharmacodynamics. This challenge makes it difficult to …

Nose-to-brain delivery is a promising way to reach the central nervous system with
therapeutic drugs. However, the location of the olfactory region at the top of the nasal cavity …

OBJECTIVE: The aim of this paper is to investigate the efficacy of filler applications which
were evaluated in terms of nasal deformity and quality of life of the patients, and to review …

Nasal irrigation (NI) is an old practice of upper respiratory tract care that likely originated in
the Ayurvedic medical tradition. It is used alone or in association with other therapies in …