Sensitivity of neurons to weak electric fields

JT Francis, BJ Gluckman, SJ Schiff - Journal of Neuroscience, 2003 - Soc Neuroscience
Weak electric fields modulate neuronal activity, and knowledge of the interaction threshold is
important in the understanding of neuronal synchronization, in neural prosthetic design, and …

Spike timing amplifies the effect of electric fields on neurons: implications for endogenous field effects

T Radman, Y Su, JH An, LC Parra… - Journal of …, 2007 - Soc Neuroscience
Despite compelling phenomenological evidence that small electric fields (< 5 mV/mm) can
affect brain function, a quantitative and experimentally verified theory is currently lacking …

Sensitivity of coherent oscillations in rat hippocampus to AC electric fields

JK Deans, AD Powell, JGR Jefferys - The Journal of physiology, 2007 - Wiley Online Library
The sensitivity of brain tissue to weak extracellular electric fields is important in assessing
potential public health risks of extremely low frequency (ELF) fields, and potential roles of …

Low-intensity electrical stimulation affects network dynamics by modulating population rate and spike timing

D Reato, A Rahman, M Bikson… - Journal of …, 2010 - Soc Neuroscience
Clinical effects of transcranial electrical stimulation with weak currents are remarkable
considering the low amplitude of the electric fields acting on the brain. Elucidating the …

Endogenous and exogenous electric fields as modifiers of brain activity: rational design of noninvasive brain stimulation with transcranial alternating current …

F Fröhlich - Dialogues in clinical neuroscience, 2014 - Taylor & Francis
Synchronized neuronal activity in the cortex generates weak electric fields that are routinely
measured in humans and animal models by electroencephalography and local field …

Measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation

Y Huang, AA Liu, B Lafon, D Friedman, M Dayan… - elife, 2017 - elifesciences.org
Transcranial electric stimulation aims to stimulate the brain by applying weak electrical
currents at the scalp. However, the magnitude and spatial distribution of electric fields in the …

Transcranial electric stimulation entrains cortical neuronal populations in rats

S Ozen, A Sirota, MA Belluscio… - Journal of …, 2010 - Soc Neuroscience
Low intensity electric fields have been suggested to affect the ongoing neuronal activity in
vitro and in human studies. However, the physiological mechanism of how weak electrical …

Endogenous cortical oscillations constrain neuromodulation by weak electric fields

SL Schmidt, AK Iyengar, AA Foulser, MR Boyle… - Brain stimulation, 2014 - Elsevier
Background Transcranial alternating current stimulation (tACS) is a non-invasive brain
stimulation modality that may modulate cognition by enhancing endogenous neocortical …

The effect of spatially inhomogeneous extracellular electric fields on neurons

CA Anastassiou, SM Montgomery… - Journal of …, 2010 - Soc Neuroscience
The cooperative action of neurons and glia generates electrical fields, but their effect on
individual neurons via ephaptic interactions is mostly unknown. Here, we analyze the impact …

Ephaptic coupling of cortical neurons

CA Anastassiou, R Perin, H Markram, C Koch - Nature neuroscience, 2011 - nature.com
The electrochemical processes that underlie neural function manifest themselves in
ceaseless spatiotemporal field fluctuations. However, extracellular fields feed back onto the …