The effects of acute myocardial infarction on the pharmacqkinetics of digoxin were studied.
Digoxin, 0.75 mg, was given orally to 12 patients with left-sided cardiac failure due to acute …

The interaction of quinidine and digoxin was studied in eight mongrel dogs with three
protocols separated by at least 4 weeks. To estimate the kinetics of digoxin alone, 0.06 …

The influence of age on tissue distribution of digoxin in mice and guinea pigs and uptake by
mouse heart slices was investigated. 4 h after a single dose of 3H-digoxin, tissue: plasma …

The in vitro dissolution and the bioavailability of two pharmaceutical formulations of digoxin
were compared, one being a common commercial tablet form and the other a solution of the …

Numerous pharmacological agents have been shown to produce clinically significant
pharmacokinetic interactions with digoxin. Drugs which reduce digoxin absorption include …

The purpose of this study was to evaluate the disposition kinetics of digoxin after the
administration of a single intravenous dose to the same dogs before and during azotemia …

The effect of potassium on the binding of digoxin or digoxigenin to isolated Na+, K+-ATPase
was compared with that of potassium on the positive inotropic action of the agents in guinea …

The steady‐state pharmacokinetics of oral digoxin in eight hospitalized patients was
compared upon their admission with marked right‐sided congestive heart failure and later …

In isolated guinea-pig left atria driven by rates of 0.5, 1, 2, 3 and 4 Hz digoxin was infused
continuously until cardiac arrest occurred. The experiments were performed in Tyrode …

The extent and time course of the reversal of digoxin-induced inotropy by digoxin-specific
antibodies and their Fab fragments were studied in seven conscious dogs instrumented with …