A typical product lifecycle stage is fraught with challenges right from the inception, ie, early
drug discovery/lead optimization to product development. Challenge includes optimization …

Introduction: Preformulation assists scientists in screening lead candidates based on their
physicochemical and biopharmaceutical properties. This data is useful for selection of new …

The physicochemical properties of pharmacological molecules have a tremendous effect on
safety and efficacy. Poor physicochemical properties can often make it hard to set up a …

Preformulation is a group of studies that focus on the physicochemical properties of a new
drug candidate that could affect the drug performance and the development of a dosage …

Discovering and developing new medicines is a long, complex and expensive process and
the failure rate is high during the process. To minimise attrition it is essential, therefore, to …

Activities done prior to formulation development are called as preformulation studies. It
provides the scientific basis for formulation development. Preformulation studies can be …

Before the development of any pharmaceutical formulation, a drug's various physiochemical
properties have to be determined to facilitate the process of development of new drug …

Drug discovery occurs in silico, in chemistry laboratories, in cell-free assays or tissue
culturesystems, or in vivo in animal models on a molecule synthesized by the chemist. Final …

It is axiomatic that the physicochemical properties of candidate drugs can influence their
subsequent development. The results of characterization studies carried out will influence …

Drugs are not administered as pure chemical drug substances but rather in a dosage form. A
dosage form sometimes known as a drug product contains many more inactive materials …