Sepsis is a life-threatening medical condition that occurs when the host has an uncontrolled
or abnormal immune response to overwhelming infection. It is now widely accepted that …

Sepsis is a life-threatening condition and a global disease burden. Today, the
heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …

Sepsis is a leading cause of death worldwide. After initial trials modulating the
hyperinflammatory phase of sepsis failed, generations of researchers have focused on …

Sepsis—which is a severe life-threatening infection with organ dysfunction—initiates a
complex interplay of host pro-inflammatory and anti-inflammatory processes. Sepsis can be …

Sepsis with subsequent multiple organ dysfunction is a pronounced systemic inflammatory
response to concealed or known infection and is a leading cause of death in intensive care …

Sepsis is an ill-defined syndrome yet is a leading cause of morbidity and mortality
worldwide. The most recent consensus defines sepsis as life-threatening organ dysfunction …

Introduction Sepsis is a dysregulated host immune response due to an uncontrolled
infection. It is a leading cause of mortality in adult intensive care units globally. When the …

Sepsis is a significant cause of death worldwide. Although the prevailing theory of the sepsis
syndrome has been that of a condition of uncontrolled inflammation in response to infection …

Infection begins when microorganisms overcome host barriers and multiply within host
tissues. To contain the infection, the host mounts an inflammatory response that mobilizes …

The clinical syndrome of sepsis encompasses a highly heterogeneous group of clinical
disorders, varying with respect to the site, bacteriology, and even presence of infection and …