Because oxidative stress is involved in the pathogenesis of various chronic diseases and
the aging process, antioxidants that can increase the intrinsic antioxidant potency are …

Nephrotoxicity is a major complication that limits the therapeutic application of cisplatin
(CIS). Oxidative stress and inflammation are implicated in CIS-induced acute kidney injury …

Renal toxicity is a serious side effect that hinders the use of cisplatin, a commonly used and
effective chemotherapeutic agent. Meanwhile, quinacrine is an FDA approved drug that has …

Although cisplatin is an effective anticancer drug, its clinical application is limited due to
various side effects, especially nephrotoxicity. In this study, we investigated the protective …

Cisplatin (CP) is a potent and widely used chemotherapeutic agent. However, the clinical
benefits of CP are compromised because it elicits nephrotoxicity and ototoxicity. In this study …

Stratifin (SFN) is a member of the 14-3-3 family of highly conserved soluble acidic proteins,
which regulates a variety of cellular activities such as cell cycle, cell growth and …

Cisplatin is one of the most effective chemotherapeutic agents; however, its clinical use is
limited by serious side effects of which nephrotoxicity is the most important. Nephrotoxicity …

Although cisplatin attacks various tumors with remarkable efficacy, its clinical usage has
been limited by its side effects, particularly nephrotoxicity. Salubrinal, a selective eukaryotic …

Background Cisplatin-induced nephrotoxicity is related to increased reactive oxygen
species and inflammatory cytokines in the kidney. Sinapic acid (SA) has both antioxidant …

Cisplatin (Cis) is one of the most potent and effective broad‐spectrum antitumor drugs, but
its use is limited due to nephrotoxicity. The current study investigated the renoprotective …