[HTML][HTML] Current concept on the pathogenesis of inflammatory bowel disease-crosstalk between genetic and microbial factors: pathogenic bacteria and altered …

PL Lakatos, S Fischer, L Lakatos, I Gal… - World Journal of …, 2006 - ncbi.nlm.nih.gov
The pathogenesis of inflammatory bowel disease (IBD) is only partially understood. Various
environmental and host (eg genetic-, epithelial-, immune and non-immune) factors are …

Inflammatory bowel disease: a complex group of genetic disorders

JP Hugot - Best Practice & Research Clinical Gastroenterology, 2004 - Elsevier
Inflammatory bowel disease (IBD) are complex genetic disorders resulting from the complex
interplay between several genetic and environmental risk factors. The number of IBD genes …

New insights into the pathophysiology of inflammatory bowel disease: microbiota, epigenetics and common signalling pathways

G Rogler, L Biedermann, M Scharl - Swiss medical weekly, 2018 - zora.uzh.ch
The exact pathophysiology of inflammatory bowel disease (IBD) is still unknown. However,
over the years important insights allowed the development of novel therapeutic approaches …

Inflammatory bowel disease and genetics

RK Weersma, HM Van Dullemen… - Alimentary …, 2007 - Wiley Online Library
Introduction Inflammatory bowel disease (IBD) comprising ulcerative colitis (UC) and
Crohn's disease (CD) is multigenic disorder. Tremendous progress has been achieved in …

[HTML][HTML] Inflammatory bowel disease: pathogenesis

YZ Zhang, YY Li - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is
characterized by chronic relapsing intestinal inflammation. It has been a worldwide health …

Molecular pathogenesis of inflammatory bowel disease: genotypes, phenotypes and personalized medicine

P Goyette, C Labbé, TT Trinh, RJ Xavier… - Annals of …, 2007 - Taylor & Francis
Crohn's disease (CD) and ulcerative colitis (UC), also known as inflammatory bowel
diseases (IBD), are characterized by chronic inflammation of the gastrointestinal tract. IBD is …

The role of genetics in inflammatory bowel disease

L Henckaerts, C Figueroa, S Vermeire… - Current drug …, 2008 - ingentaconnect.com
The volume of research undertaken on the genetic susceptibility of inflammatory bowel
disease (IBD) has been tremendous. Genome-wide linkage studies pointed towards more …

Update on genetics in inflammatory disease

CG Noomen, DW Hommes, HH Fidder - Best Practice & Research Clinical …, 2009 - Elsevier
Crohn's disease and ulcerative colitis are chronic inflammatory disorders caused by a
disruptive interaction between the immune system and gut luminal factors. Although the …

The genetics of inflammatory bowel disease

DK Bonen, JH Cho - Gastroenterology, 2003 - Elsevier
The inflammatory bowel diseases (IBD) comprise complex genetic disorders, with multiple
contributing genes. Linkage studies have implicated several genomic regions as likely …

The genetic architecture of inflammatory bowel disease: past, present and future

I Cleynen, S Vermeire - Current opinion in gastroenterology, 2015 - journals.lww.com
Genetic, transcriptomic and epigenetic studies have offered exciting clues about IBD
pathogenesis but are unlikely to provide all answers. To fully grasp the function of disease …