Combination therapy has shown an obvious efficacy on complex diseases and can greatly
reduce the development of drug resistance. However, even with high-throughput screens …

Drug combination is now a hot research topic in the pharmaceutical industry, but experiment-
based methodologies are extremely costly in time and money. Many computational methods …

Drug combination is a sensible strategy for disease treatment because it improves the
treatment efficacy and reduces concomitant side effects. Due to the large number of possible …

Combinatorial therapy is a promising strategy for combating complex disorders due to
improved efficacy and reduced side effects. However, screening new drug combinations …

Synergistic effects between drugs are rare and highly context-dependent and patient-
specific. Hence, there is a need to develop novel approaches to stratify patients for optimal …

Combinatorial therapy may reduce drug side effects and improve drug efficacy, making
combination therapy a promising strategy to treat complex diseases. However, in the …

Drug combinations have been proposed as a promising therapeutic strategy to overcome
drug resistance and improve efficacy of monotherapy regimens in cancer. This strategy aims …

Drug combination therapies have been a viable strategy for the treatment of complex
diseases such as cancer due to increased efficacy and reduced side effects. However …

Drug combinations have exhibited promising therapeutic effects in treating cancer patients
with less toxicity and adverse side effects. However, it is infeasible to experimentally screen …

Combination therapy has shown an obvious curative effect on complex diseases, whereas
the search space of drug combinations is too large to be validated experimentally even with …