Type I interferons (IFNs)(IFN-α, IFN-β) and type III IFNs (IFN-λ) share many properties,
including induction by viral infection, activation of shared signaling pathways, and …

Type I interferons (IFNs) are a family of cytokines specialized to coordinate immunity to
viruses and other intracellular infections. In the past several years, many of the receptors …

Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes: Cell Skip
to Main Content Advertisement Cell This journal offers authors two options (open access or …

Type I IFNs (α, β, and others) are a family of cytokines that are produced in physiological
conditions as well as in response to the activation of pattern recognition receptors. They are …

IFNs are comprised of three families of cytokines that confer protection against pathogen
infection and uncontrolled cellular proliferation. The broad role IFNs play in innate and …

Type III interferons (IFNs)(or IFN-λ) are the latest addition to the IFN family. Even though they
share little protein homology with type I IFN, both exhibit remarkable functional similarities …

Type III interferons (IFNs) or the lambda IFNs (IFNLs or IFN-λs) are antimicrobial cytokines
that play key roles in immune host defense at endothelial and epithelial barriers. IFNLs …

Type I interferons (IFN-I) were first discovered as an antiviral factor by Isaacs and
Lindenmann in 1957, but they are now known to also modulate innate and adaptive …

Type I interferons (IFNs), which include the IFN-α s, IFN-β, IFN-ω, IFN-κ, and IFN-τ, are an
evolutionarily conserved group of secreted cytokines that serve as potent extracellular …

Type I interferon (IFN), as its name implies,'interferes' with virus replication by activating
numerous genes. Further, virus-induced type I IFN regulates the magnitude and functions of …