A near-infrared organoplatinum (II) metallacycle conjugated with heptamethine cyanine for trimodal cancer therapy

B Huang, X Liu, G Yang, J Tian, Z Liu, Y Zhu… - CCS …, 2022 - chinesechemsoc.org
Discrete Pt (II) metallacycles have attracted particular attention for the chemotherapeutic
treatment of cancer. However, a single chemotherapy cannot simultaneously balance …

An NIR Discrete Metallacycle constructed from Perylene Bisimide and Tetraphenylethylene Fluorophores for imaging‐guided cancer Radio‐chemotherapy

Y Ding, Z Tong, L Jin, B Ye, J Zhou, Z Sun… - Advanced …, 2022 - Wiley Online Library
To promote the clinical theranostic performances of platinum‐based anticancer drugs,
imaging capability is urgently desired, and their chemotherapeutic efficacy needs to be …

Stable and well-organized near-infrared platinum (II)–Acetylide-Based metallacycles-mediated cancer phototherapy

G Li, X Zhang, W Zhao, W Zhao, F Li… - … applied materials & …, 2020 - ACS Publications
The development of metallacycles with high stability and intense near-infrared (NIR)
absorption is important for biomedical applications. However, very few molecular design …

Tumor‐Targeting Near‐Infrared Dimeric Heptamethine Cyanine Photosensitizers with an Aromatic Diphenol Linker for Imaging‐Guided Cancer Phototherapy

Y Xu, J Yu, J Hu, K Sun, W Lu, F Zeng… - Advanced …, 2023 - Wiley Online Library
Phototherapy is considered a promising alternative to conventional tumor treatments due to
its noninvasive modality and effective therapeutic effect. However, designing a …

Mitochondria‐targeted small‐molecule fluorophores for dual modal cancer phototherapy

S Luo, X Tan, S Fang, Y Wang, T Liu… - Advanced Functional …, 2016 - Wiley Online Library
Mitochondria are recognized as the ideal target for cancer treatment because they play a
central role in oxidative metabolism and apoptosis. In this work, a mitochondria‐targeted …

Phototheranostic agents based on nonionic heptamethine cyanine for realizing synergistic cancer phototherapy

T Liu, Y Chen, H Wang, M Cui, J Zhang… - Advanced …, 2023 - Wiley Online Library
Asymmetrical heptamethine cyanine with near‐infrared (NIR) absorption is used for
photothermal therapy (PTT) of cancer. Aiming to overcome the drawbacks caused by the …

Heptamethine Cyanine‐Based Nanotheranostics with Catalase‐Like Activity for Synergistic Phototherapy of Cancer

M Liang, X Mu, Y Li, Y Tan, X Hao… - Advanced Functional …, 2023 - Wiley Online Library
Single‐molecule photosensitizers (PSs) for synergistic phototherapy are desirable but highly
challenging, due to the competitive relationship between photothermal (PTT) and …

Three birds with one stone: acceptor engineering of hemicyanine dye with NIR‐II emission for synergistic photodynamic and photothermal anticancer therapy

W Cao, Y Zhu, F Wu, Y Tian, Z Chen, W Xu, S Liu, T Liu… - Small, 2022 - Wiley Online Library
It is challenging to develop a near‐infrared (NIR) small molecular photosensitizer for
synergistic phototherapy in deep tissues. Herein, first, a heavy‐atom‐free NIR hemicyanine …

A tumor-targeting near-infrared heptamethine cyanine photosensitizer with twisted molecular structure for enhanced imaging-guided cancer phototherapy

X Zhao, H Zhao, S Wang, Z Fan, Y Ma… - Journal of the …, 2021 - ACS Publications
In recent years, cancer phototherapy has been extensively studied as noninvasive cancer
treatment. To present efficient recognition toward cancer cells, most photosensitizers (PSs) …

The AIE‐active dual‐cationic molecular engineering: synergistic effect of dark toxicity and phototoxicity for anticancer therapy

Y Ma, Z Zhuang, L Xing, J Li, Z Yang… - Advanced Functional …, 2021 - Wiley Online Library
The development of anticancer therapy is significant to human health but remains a huge
challenge. Photodynamic therapy (PDT), inducing the synergistic mitochondrial dysfunction …