Genkwanin ameliorates adjuvant-induced arthritis in rats through inhibiting JAK/STAT and NF-κB signaling pathways

Y Bao, YW Sun, J Ji, L Gan, CF Zhang, CZ Wang… - Phytomedicine, 2019 - Elsevier
Background Genkwanin is a flavone isolated from the traditional Chinese herb Daphne
genkwa. Our previous work proved that four flavonoids (including genkwanin) isolated from …

Anti-rheumatoid arthritis effects of flavonoids from Daphne genkwa

Y Sun, Y Bao, H Yu, Q Chen, F Lu, S Zhai… - International …, 2020 - Elsevier
Objective This study aims to select the most effective anti-Rheumatoid Arthritis (RA)
component of flavonoids from Daphne genkwa Sieb. et Zucc. by anti-inflammatory and …

Anti-rheumatoid arthritic activity of flavonoids from Daphne genkwa

CP Jiang, X He, XL Yang, SL Zhang, H Li, ZJ Song… - Phytomedicine, 2014 - Elsevier
The aim of the study was to investigate the anti-rheumatoid arthritic activity of four flavonoids
from Daphne genkwa (FFD) in vivo and in vitro. Flavonoids of D. genkwa were extracted by …

Anti-rheumatoid arthritis effects of traditional Chinese herb couple in adjuvant-induced arthritis in rats

T Pan, T Cheng, Y Jia, P Li, F Li - Journal of Ethnopharmacology, 2017 - Elsevier
Abstract Ethnopharmacological relevance Clematis chinensis Osbeck/Notopterygium
incisum Ting ex H, T-Chang (CN) is a traditional Chinese herb couple with prominent …

Gentiopicroside attenuates collagen-induced arthritis in mice via modulating the CD147/p38/NF-κB pathway

N Jia, H Ma, T Zhang, L Wang, J Cui, Y Zha… - International …, 2022 - Elsevier
Gentiopicroside (GEN) is a secoiridoid glycosides isolated from a traditional Chinese
medicine Gentiana macrophylla Pall.. It exhibits potential activities in the treatment of …

Wutou decoction ameliorates experimental rheumatoid arthritis via regulating NF-kB and Nrf2: integrating efficacy-oriented compatibility of traditional Chinese …

Y Xie, CT Mai, DC Zheng, YF He, SL Feng, YZ Li… - Phytomedicine, 2021 - Elsevier
Background Thousands of years of clinical application of Wutou decoction (WTD) support its
reliable efficacy and safety in treating rheumatoid arthritis (RA). However, the underlying …

Antioxidant effects of Genkwa flos flavonoids on Freund׳ s adjuvant-induced rheumatoid arthritis in rats

CF Zhang, SL Zhang, X He, XL Yang, HT Wu… - Journal of …, 2014 - Elsevier
Abstract Ethnopharmacological relevance Genkwa flos (Daphne genkwa Sieb. et Zucc.), a
Chinese herbal medicine, has been traditionally used for over two thousand years in China …

Diosmetin exhibits anti‐proliferative and anti‐inflammatory effects on TNF‐α‐stimulated human rheumatoid arthritis fibroblast‐like synoviocytes through regulating the …

Y Chen, Y Wang, M Liu, B Zhou… - Phytotherapy …, 2020 - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by inflammation
and proliferation of synovial tissues. Diosmetin is a bioflavonoid possessing an anti …

Kadsura heteroclita stem suppresses the onset and progression of adjuvant-induced arthritis in rats

H Yu, R Zeng, Y Lin, X Li, S Tasneem, Z Yang, Y Qiu… - Phytomedicine, 2019 - Elsevier
Background Rheumatoid arthritis (RA) is a chronic autoimmune diseased state,
characterized by hyperplasia of the synovial membrane, degradation of cartilage, and bone …

Curculigoside exerts significant anti‑arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF‑κB signaling pathway

S Tan, J Xu, A Lai, R Cui, R Bai… - Molecular …, 2019 - spandidos-publications.com
The present study aimed to investigate the anti‑arthritic effects of curculigoside isolated from
the rhizome of Curculigo orchioides Gaertn in vivo and in vitro, as well as to determine the …