This study examines the mechanisms by which brinzolamide reduces intraocular pressure
(IOP) in healthy rabbits and in monkeys with unilateral ocular hypertension. Intraocular …

Importance This study evaluates the contribution of the individual components of an
investigational non–β-antagonist fixed combination of brinzolamide, 1%, and brimonidine …

Aim: A prospective, randomised study to evaluate effects of brinzolamide on ocular
haemodynamics in healthy volunteers. Methods: 30 volunteers (12 men, 18 women; 28.3 …

OBJECTIVE: To compare the efficacy and safety of a fixed combination of 2.0% dorzolamide
and 0.5% timolol administered twice daily with each of the individual components …

The aim of this study was to evaluate the effects of brimonidine 0.2% and dorzolamide 2%
on the ocular blood flow velocity in patients with newly diagnosed primary open-angle …

Purpose To compare the efficacy of brinzolamide versus placebo when added to
travoprost/timolol fixed combination (TTFC) in uncontrolled patients. Patients and Methods …

OBJECTIVE: To compare the efficacy of combinations of betaxolol-brinzolamide and timolol-
dorzolamide as suppressors of aqueous humor flow and ocular hypotensive agents …

Background The purpose of this study was to assess the safety and efficacy of fixed-
combination brinzolamide 1%/timolol 0.5%(BRINZ/TIM-FC) compared with concomitant …

PURPOSE: The aim was to compare topical brinzolamide 1% twice daily with dorzolamide
2% twice daily, each given with timolol 0.5% twice daily, for safety and effects on intraocular …

Brimonidine, a highly selective α2-adrenoceptor agonist, was studied to determine its ocular
hypotensive effect and side effects in patients with elevated intraocular pressure (IOP) while …