Since the discovery of interferons over 50 years ago, efforts to understand the biochemistry,
molecular biology and biological activities of cytokines have been intense and rewarding …

IL-17 is the defining cytokine of a newly-described “Th17” population that plays critical roles
in mediating inflammation and autoimmunity. The IL-17/IL-17 receptor superfamily is the …

The IL-17/IL-17 receptor family is the newest and least understood of the cytokine
subclasses. Composed of ligands IL-17A-IL-17F and receptors IL-17RA-IL-17RE, these …

Abstract Interleukin-17A (IL-17A), the hallmark cytokine of the newly defined T helper 17
(TH17) cell subset, has important roles in protecting the host against extracellular …

Abstract The interleukin-17 (IL-17) family comprises six members (IL-17A–17F), and
recently, all of its related receptors have been discovered. IL-17 was first discovered …

Recently, the IL-17 family member cytokines have become prominent subjects of
investigation. IL-17 (IL-17A) is the best-described member of this family where its production …

Abstract Interleukin-17 (IL-17) and IL-17-producing cells have been shown to play important
roles in inflammation and the immune response. IL-17 is believed to be mainly produced by …

Abstract Interleukin-17 (IL-17) is a prototype member of a new cytokine family with six
species identified to date. IL-17 is secreted mainly by activated CD4+ and CD8+ T …

Interleukin 17 (IL-17) and its closest relative, IL-17F, have recently drawn much attention in
the field of immunology. IL-17 and IL-17F are expressed by a distinct type of T cells, T helper …

Interleukin-17A (IL-17A) is the signature cytokine of the recently identified T helper 17 (Th17)
cell subset. IL-17 has six family members (IL-17A to IL-17F). Although IL-17A and IL-17F …