Obesity and cancer: the role of dysfunctional adipose tissue
RCM Van Kruijsdijk, E Van Der Wall… - … , biomarkers & prevention, 2009 - AACR
Overweight and obesity are health problems of epidemic proportions, increasing the risk not
only of cardiovascular disease and type 2 diabetes mellitus but also of various types of …
only of cardiovascular disease and type 2 diabetes mellitus but also of various types of …
Molecular mechanisms of cancer development in obesity
MJ Khandekar, P Cohen, BM Spiegelman - Nature Reviews Cancer, 2011 - nature.com
The increasing incidence of obesity and its co-morbid conditions poses a great challenge to
global health. In addition to cardiovascular disease and diabetes, epidemiological data …
global health. In addition to cardiovascular disease and diabetes, epidemiological data …
Obesity, adipokines and cancer: an update
CH Lee, YC Woo, Y Wang, CY Yeung… - Clinical …, 2015 - Wiley Online Library
Obesity causes dysfunction of adipose tissue, with resultant chronic inflammation and
adverse interplay of various adipokines, sex steroids and endocrine hormones. All these …
adverse interplay of various adipokines, sex steroids and endocrine hormones. All these …
Insights into the link between obesity and cancer
SE Ackerman, OA Blackburn, F Marchildon… - Current obesity …, 2017 - Springer
Abstract Purpose of Review Adipocytes have adapted to store energy in the form of lipid and
also secrete circulating factors called adipokines that signal to other tissues to coordinate …
also secrete circulating factors called adipokines that signal to other tissues to coordinate …
Update on adipose tissue and cancer
KA Brown, PE Scherer - Endocrine reviews, 2023 - academic.oup.com
Adipose tissue is the largest endocrine organ and an accepted contributor to overall energy
homeostasis. There is strong evidence linking increased adiposity to the development of 13 …
homeostasis. There is strong evidence linking increased adiposity to the development of 13 …
Adipose tissue, obesity and adipokines: role in cancer promotion
A Booth, A Magnuson, J Fouts… - … molecular biology and …, 2015 - degruyter.com
Adipose tissue is a complex organ with endocrine, metabolic and immune regulatory roles.
Adipose depots have been characterized to release several adipocytokines that work locally …
Adipose depots have been characterized to release several adipocytokines that work locally …
[HTML][HTML] Mechanisms linking excess adiposity and carcinogenesis promotion
AI Pérez-Hernández, V Catalán… - Frontiers in …, 2014 - frontiersin.org
Obesity constitutes one of the most important metabolic diseases being associated to insulin
resistance development and increased cardiovascular risk. Association between obesity …
resistance development and increased cardiovascular risk. Association between obesity …
Signals from the adipose microenvironment and the obesity–cancer link—a systematic review
Obesity and its associated metabolic dysregulation are established risk factors for many
cancers. However, the biologic mechanisms underlying this relationship remain …
cancers. However, the biologic mechanisms underlying this relationship remain …
From obesity to cancer: a review on proposed mechanisms
Nowadays, obesity is considered as a serious and growing global health problem. It is
documented that the overweight and obesity are major risk factors for a series of …
documented that the overweight and obesity are major risk factors for a series of …
Visceral adiposity, insulin resistance and cancer risk
CL Donohoe, SL Doyle, JV Reynolds - Diabetology & metabolic syndrome, 2011 - Springer
Background There is a well established link between obesity and cancer. Emerging
research is characterising this relationship further and delineating the specific role of excess …
research is characterising this relationship further and delineating the specific role of excess …