The objective of this review was to evaluate the potential of tauroursodeoxycholic acid
(TUDCA) for neuroprotection in traumatic brain injury (TBI) patients in the neurocritical care …

Tauroursodeoxycholic acid (TUDCA), an endogenous bile acid, modulates cell death by
interrupting classic pathways of apoptosis. Intracerebral hemorrhage (ICH) is a devastating …

Most neurodegenerative disorders are diseases of protein homeostasis, with misfolded
aggregates accumulating. The neurodegenerative process is mediated by numerous …

Greater clinical understanding of the pivotal role of apoptosis in spinal cord injury (SCI) has
led to new and innovative apoptosis-based therapies for patients with an SCI …

Background Tauroursodeoxycholic acid (TUDCA) is a hydrophilic bile acid derivative, which
has been demonstrated to have neuroprotective effects in different neurological disease …

Traumatic brain injury (TBI) is one of the leading causes of trauma-induced mortality and
disability, and emerging studies have shown that endoplasmic reticulum (ER) stress plays …

Ursodeoxycholic acid (UDCA) is a bile acid component with anti-apoptotic, anti-oxidant and
anti-inflammatory properties. It has been used in clinical medicine for liver diseases for …

Tauroursodeoxycholic acid (TUDCA), a hydrophilic bile acid, is a strong modulator of
apoptosis in both hepatic and nonhepatic cells, and appears to function by inhibiting …

Background Bile acids are steroid acids found predominantly in the bile of mammals. The
bile acid conjugate tauroursodeoxycholic acid (TUDCA) is a neuroprotective agent in …

Accumulating evidence has shown that tauroursodeoxycholic acid (TUDCA) is
neuroprotective in different animal models of neurological diseases. However, whether …