N-methyl-N-nitrosourea (NMU) is widely used to model oxidative stress and inflammation
mediated retinal neurodegeneration. Wedelolactone (WD) is known to have antioxidant, anti …

Background Retinal ischemia–reperfusion (RIR) injury refers to an obstruction in the retinal
blood supply followed by reperfusion. Although the molecular mechanism underlying the …

Age-related macular degeneration (AMD) is the leading cause of low vision and blindness
for which there is currently no cure. Increased matrix metalloproteinase-9 (MMP-9) was …

Glaucoma is a leading cause of permanent blindness worldwide and is characterized by
neurodegeneration linked to progressive retinal ganglion cell (RGC) death, axonal damage …

Apoptotic death of retinal ganglion cells (RGCs) is a common pathologic feature in different
types of optic neuropathy, including ischemic optic neuropathy and glaucoma, ultimately …

Retinitis pigmentosa (RP) is an inherited photoreceptor-degenerative disease, and neuronal
degeneration in RP is exacerbated by glial activation. Cassia seed (Jue-ming-zi) is a …

Dry age-related macular degeneration (AMD) is a type of disease that causes visual
impairment due to changes in the macula located in the center of the retina. The …

Aims Retinal ischemia/reperfusion (I/R) injury is common in the development of ophthalmic
diseases and potentially causes blindness. In present study, the aim is to investigate the …

Vision impairment in retinal degenerative diseases such as age-related macular
degeneration is primarily associated with photoreceptor degeneration, in which oxidative …

Background Retinal degenerative diseases significantly contribute to visual impairment and
blindness. Microglia reactivity is a hallmark of neurodegenerative diseases including retinal …