Acetylcholine (ACh) is believed to act as a neuromodulator in cortical circuits that support
cognition, specifically in processes including learning, memory consolidation, vigilance …

Acetylcholine (ACh) signaling shapes neuronal circuit development and underlies specific
aspects of cognitive functions and behaviors, including attention, learning, memory and …

The neocortex is densely innervated by basal forebrain (BF) cholinergic neurons. Long-
range axons of cholinergic neurons regulate higher-order cognitive function and dysfunction …

Acetylcholine regulates the cerebral cortex to sharpen sensory perception and enhance
attentional focus. The cellular and circuit mechanisms of this cholinergic modulation are …

ACh is a signaling molecule in the mammalian CNS, with well-documented influence over
cognition and behavior. However, the nature of cholinergic signaling in the brain remains …

Rat and mouse models are widely used for studies in cognition and pathophysiology,
among others. Here, we sought to determine to what extent these two model species differ …

Acetylcholine (ACh) is an important neurotransmitter of the CNS that binds both nicotinic and
muscarinic receptors to exert its action. However, the mechanisms underlying the effects of …

Cholinergic neurons in the medial septum (MS) constitute a major source of cholinergic
input to the forebrain and modulate diverse functions, including sensory processing …

Basal forebrain cholinergic neurons influence cortical state, plasticity, learning, and
attention. They collectively innervate the entire cerebral cortex, differentially controlling …

Acetylcholine (ACh) can act on pre-and post-synaptic muscarinic receptors (mAChR) in the
cortex to influence a myriad of cognitive processes. Two functionally-distinct regions of the …