Forkhead O transcription factors (FOXO) are critical for the regulation of cell cycle arrest, cell
death, and DNA damage repair. Inactivation of FOXO proteins may be associated with …

The transcription factor Forkhead box M1 (FOXM1) is a key regulator of cell proliferation and
is overexpressed in many forms of primary cancers, leading to uncontrolled cell division and …

BACKGROUND: The transcription factor Forkhead box M1 (FoxM1) is known to play an
important role in the development and progression of many malignancies including lung …

Background Cisplatin (CDDP) is one of the most important chemotherapeutic agents in the
treatment of advanced gastric cancer, but its efficacy is limited by CDDP resistance. Because …

Aim Deregulation of FOXM1 has been documented in various cancers. The aim of this study
was to evaluate the role of FOXM1 in ovarian cancer tumorigenesis and paclitaxel …

Forkhead box C1 (FOXC1) is an essential member of the forkhead box transcription factors
and has been highlighted as an important transcriptional regulator of crucial proteins …

The forkhead box O (FOXO) transcription factors are considered as tumor suppressors that
limit cell proliferation and induce apoptosis. FOXO gene alterations have been described in …

Forkhead box transcription factor, FOXM1 is implicated in several cellular processes such as
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …

Chemotherapy regimens containing cisplatin remain the first-line treatments for patients with
oral squamous cell cancer (OSCC); however, the treatment effect is often transient because …

Cisplatin is a conventional chemotherapeutic agent that binds covalently to purine DNA
bases and mediates cellular apoptosis. A better understanding of the downstream cellular …