Genome-editing tools, which include zinc finger nucleases (ZFNs), transcription activator-
like effector nucleases (TALENs), and clustered regularly interspaced short palindromic …

Abstract Purpose of Review The opportunities afforded through the recent advent of genome-
editing technologies have allowed investigators to more easily study a number of diseases …

During the past decade, developments in genome editing technology have fundamentally
transformed biomedical research. In particular, the CRISPR/Cas9 system has been …

A variety of genetic cardiovascular diseases may one day be curable using gene editing
technology. Germline genome editing and correction promises to permanently remove …

Genome‐editing technology has emerged as a powerful method that enables the generation
of genetically modified cells and organisms necessary to elucidate gene function and …

Cardiovascular diseases are among the main causes of morbidity and mortality in Western
countries and considered as a leading public health issue. Therefore, there is a strong need …

The rapid development of genome editing technology has brought major breakthroughs in
the fields of life science and medicine. In recent years, the clustered regularly interspaced …

Cardiovascular disease remains the leading cause of morbidity and mortality in the
developed world. In recent decades, extraordinary effort has been devoted to defining the …

Although human genetics has resulted in the identification of novel lipid-related genes that
can be targeted for the prevention of atherosclerotic vascular disease, medications targeting …

Many novel CRISPR-based genome-editing tools, with a wide variety of applications, have
been developed in the past few years. The original CRISPR–Cas9 system was developed …