[HTML][HTML] Illuminating (HTLV-1)-induced adult T-cell leukemia/lymphoma transcriptomic signature: A systems virology approach
MM Forghani-Ramandi, B Mostafavi, A Bahavar… - Virus Research, 2023 - Elsevier
Background Adult T-cell leukemia/lymphoma (ATLL) is a poor prognosis malignancy of
peripheral T-cells caused by human T-cell leukemia virus type 1 (HTLV-1). The low survival …
peripheral T-cells caused by human T-cell leukemia virus type 1 (HTLV-1). The low survival …
[HTML][HTML] Potential miRNA-gene interactions determining progression of various ATLL cancer subtypes after infection by HTLV-1 oncovirus
MZ Ghobadi, E Afsaneh, R Emamzadeh… - BMC Medical …, 2023 - Springer
Abstract Background Adult T-cell Leukemia/Lymphoma (ATLL) is a rapidly progressing type
of T-cell non-Hodgkin lymphoma that is developed after the infection by human T-cell …
of T-cell non-Hodgkin lymphoma that is developed after the infection by human T-cell …
Signaling factors potentially associated to the pathogenesis of adult T-cell leukemia/lymphoma: a network-analysis and novel findings assessment
SH Mozhgani, MZ Ghobadi, M Norouzi, H Rahimi… - Virus research, 2022 - Elsevier
Adult T-cell leukemia/lymphoma (ATLL) is a human T-cell leukemia virus (HTLV) type 1-
associated disease of TCD4+ cell transformation. Despite extensive studies on ATLL …
associated disease of TCD4+ cell transformation. Despite extensive studies on ATLL …
[HTML][HTML] Comprehensive high-throughput meta-analysis of differentially expressed microRNAs in transcriptomic datasets reveals significant disruption of MAPK/JNK …
S Shadabi, N Delrish, M Norouzi, M Ehteshami… - Infectious Agents and …, 2021 - Springer
Background Human T-lymphotropic virus 1 (HTLV-1) infection may lead to the development
of Adult T-cell leukemia/lymphoma (ATLL). To further elucidate the pathophysiology of this …
of Adult T-cell leukemia/lymphoma (ATLL). To further elucidate the pathophysiology of this …
[HTML][HTML] Exploration of mRNAs and miRNA classifiers for various ATLL cancer subtypes using machine learning
MZ Ghobadi, R Emamzadeh, E Afsaneh - BMC cancer, 2022 - Springer
Abstract Background Adult T-cell Leukemia/Lymphoma (ATLL) is a cancer disease that is
developed due to the infection by human T-cell leukemia virus type 1. It can be classified …
developed due to the infection by human T-cell leukemia virus type 1. It can be classified …
[HTML][HTML] Clinical applications of genomic alterations in ATLL: predictive markers and therapeutic targets
N Yoshida, H Miyoshi, K Ohshima - Cancers, 2021 - mdpi.com
Simple Summary In this review paper, we aim to summarize recent findings of genomic
alterations found in adult T-cell leukemia/lymphoma (ATLL), which is an incurable disease …
alterations found in adult T-cell leukemia/lymphoma (ATLL), which is an incurable disease …
Gene biomarkers and classifiers for various subtypes of HTLV-1-caused ATLL cancer identified by a combination of differential gene co‑expression and support vector …
M Zarei Ghobadi, E Afsaneh, R Emamzadeh - Medical Microbiology and …, 2023 - Springer
Adult T-cell leukemia/lymphoma (ATLL) is pathogen-caused cancer that is progressed after
the infection by human T-cell leukemia virus type 1. Four significant subtypes comprising …
the infection by human T-cell leukemia virus type 1. Four significant subtypes comprising …
[HTML][HTML] HTLV-1-infected CD4+ T-cells display alternative exon usages that culminate in adult T-cell leukemia
M Thénoz, C Vernin, H Mortada, M Karam, C Pinatel… - Retrovirology, 2014 - Springer
Background Reprogramming cellular gene transcription sustains HTLV-1 viral persistence
that ultimately leads to the development of adult T-cell leukemia/lymphoma (ATLL). We …
that ultimately leads to the development of adult T-cell leukemia/lymphoma (ATLL). We …
[HTML][HTML] Transcriptome and Somatic Mutation Associated with Non-Malignant Human T Lymphotropic Virus Type 1 Infection and Adult T-Cell Leukemia/Lymphoma
Aggressive Adult T-cell leukemia/lymphoma (ATL), a human T lymphotropic virus type 1
(HTLV-1)-associated disease, has a poor prognosis. There is an urgent need for effective …
(HTLV-1)-associated disease, has a poor prognosis. There is an urgent need for effective …
[HTML][HTML] HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma
Human T cell leukemia virus type 1 (HTLV-1) mainly infects CD4+ T cells and induces
chronic, persistent infection in infected individuals, with some developing adult T cell …
chronic, persistent infection in infected individuals, with some developing adult T cell …