Differential requirements for activation of integrated and transiently transfected human T-cell leukemia virus type 1 long terminal repeat

M Okada, KT Jeang - Journal of virology, 2002 - Am Soc Microbiol
Adult T-cell leukemia (ATL) cells contain integrated human T-cell leukemia virus type 1
(HTLV-1) proviruses. Although the exact sequence of events leading to the development of …

[HTML][HTML] Role of miRNAs in human T cell leukemia virus type 1 induced T cell leukemia: a literature review and bioinformatics approach

CB Machado, LS da Cunha, JHS Maués… - International Journal of …, 2022 - mdpi.com
Human T cell leukemia virus type 1 (HTLV-1) was identified as the first pathogenic human
retrovirus and is estimated to infect 5 to 10 million individuals worldwide. Unlike other …

[HTML][HTML] Temporal regulation of HTLV-2 expression in infected cell lines and patients: evidence for distinct expression kinetics with nuclear accumulation of APH-2 …

C Bender, F Rende, A Cotena, P Righi, P Ronzi… - Retrovirology, 2012 - Springer
Background Human T-cell leukemia virus types 1 and 2 (HTLV-1 and HTLV-2) are delta
retroviruses with similar genetic organization. Although both viruses immortalize T-cells in …

Cumulative kinetics of epigenetic abnormalities during initiation and progression of Adult T-cell Leukemia/Lymphoma (ATLL)

T Oka, H Sato, LA Al-Kader, Y Shinnou, K Washio… - Retrovirology, 2011 - Springer
HTLV-1 causes ATLL in 3-5% of infected individuals after a long latent period of 40-60
years. ATLL is divided into four stages: namely, smoldering, chronic, lymphoma and acute …

Modulation of innate immune responses during human T-cell leukemia virus (HTLV-1) pathogenesis

S Olière, R Douville, A Sze, SM Belgnaoui… - Cytokine & growth factor …, 2011 - Elsevier
Infection with the Human T-cell Leukemia virus type I (HTLV-1) retrovirus results in a number
of diverse pathologies, including the aggressive, fatal T-cell malignancy adult T-cell …

[HTML][HTML] Development of dynamical network biomarkers for regulation in Epstein-Barr virus positive peripheral T cell lymphoma unspecified type

D Shen, Y Hong, Z Feng, X Chen, Y Cai, Q Peng… - Frontiers in …, 2022 - frontiersin.org
Background: This study was performed to identify key regulatory network biomarkers
including transcription factors (TFs), miRNAs and lncRNAs that may affect the oncogenesis …

In vivo analysis of replication and immunogenicity of proviral clones of human T-lymphotropic virus type 1 with selective envelope surface-unit mutations

LR Silverman, AJ Phipps, A Montgomery, S Fernandez… - Blood, 2005 - ashpublications.org
Human T-cell leukemia virus type 1 (HTLV-1) is a complex retrovirus etiologically linked with
adult T-cell leukemia/lymphoma (ATL), HTLV-1–associated myelopathy/tropical spastic …

The genomic landscape of adult T cell leukemia/lymphoma

C Vicente, J Cools - Nature genetics, 2015 - nature.com
Adult T cell leukemia/lymphoma (ATL) is a neoplasm linked to human T-lymphotropic virus
type-1 (HTLV-1) infection and is refractory to current combination chemotherapy. A large …

[HTML][HTML] Understanding the Immunopathology of HTLV-1-Associated Adult T-Cell Leukemia/Lymphoma: A Comprehensive Review

S Nakahata, D Enriquez-Vera, MI Jahan, K Sugata… - Biomolecules, 2023 - mdpi.com
Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL).
HTLV-1 carriers have a lifelong asymptomatic balance between infected cells and host …

Comparison of the Genetic Organization, Expression Strategies and Oncogenic Potential of HTLV‐1 and HTLV‐2

F Rende, I Cavallari, MG Romanelli… - Leukemia Research …, 2012 - Wiley Online Library
Human T cell leukemia virus types 1 and 2 (HTLV‐1 and HTLV‐2) are genetically related
complex retroviruses that are capable of immortalizing human T‐cells in vitro and establish …