New concepts in the pathogenesis, diagnosis, prognostic factors and clinical presentation of chronic lymphocytic leukemia

M Hallek - Reviews in Clinical and Experimental Hematology, 2000 - Wiley Online Library
Chronic lymphocytic leukemia of the B‐cell type CLL) is the most frequent leukemia in the
Western hemisphere. Recent advances in the understanding of the pathogenesis of this …

Molecular basis of pathogenesis, prognosis and therapy in chronic lymphocytic leukaemia

J Chen, NAJ McMillan - Cancer biology & therapy, 2008 - Taylor & Francis
B-cell chronic lymphocytic leukemia (CLL) is caused by the abnormal accumulation of non-
functional B-cells in peripheral blood and bone marrow. However, the precise aetiology and …

[图书][B] Chronic Lymphocytic Leukemia

P Oppezzo - 2012 - books.google.com
B-cell chronic lymphocytic leukemia (CLL) is considered a single disease with extremely
variable course, and survival rates ranging from months to decades. It is clear that clinical …

1 Progress in chronic lymphocytic leukaemia: A historical perspective

KR Rai - Baillière's clinical haematology, 1993 - Elsevier
A historical review of gains in the body of knowledge on chronic lymphocytic leukaemia
(CLL) reveals a continuous, steady process from the beginning of the century with the …

Chronic lymphocytic leukaemia: clinical translations of biological features

TJ Hamblin - Chronic Lymphocytic Leukemia, 2005 - Springer
The chronic lymphatic leukaemia (CLL) world was surprised to find that the disease split so
neatly down the middle into those patients with unmutated immunoglobulin genes who were …

[PDF][PDF] Chronic lymphocytic leukemia

G Dighiero, JL Binet - Hematology and cell therapy, 1996 - redbook.streamliners.co.nz
Chronic lymphocytic leukemia (CLL) follows an extremely variable course with survival
ranging from months to decades. Recently, there has been major progress in the …

Novel insights in chronic lymphocytic leukemia: are we getting closer to understanding the pathogenesis of the disease?

F Caligaris-Cappio, P Ghia - Journal of Clinical Oncology, 2008 - ascopubs.org
Chronic lymphocytic leukemia (CLL) has unique epidemiologic, biologic, and clinical
features. The progressively emerging picture leads us to consider that the critical genes for …

Pathologic and molecular genetic features of chronic lymphocytic leukemia

ED Hsi - Seminars in oncology, 2012 - Elsevier
Chronic lymphocytic leukemia (CLL) is an indolent B-cell leukemia. While many patients
may not require therapy, some patients will suffer a progressive course and die of their …

Chronic lymphocytic leukemia

T Hamblin, A Hamblin - Advances in Malignant Hematology, 2011 - Wiley Online Library
A newly discovered heterogeneity has awakened interest in chronic lymphocytic leukemia
(CLL). This has proved to be the key to unlocking the pathophysiology of the condition. A …

Morphological and immunophenotypic features of chronic lymphocytic leukemia

E Matutes, A Polliack - Reviews in clinical and experimental …, 2000 - Wiley Online Library
In this review, we summarize the morphological features and immunophenotypic profile of
chronic lymphocytic leukemia (CLL) cells, discuss the value of these investigations as front …