Acid-sensing ion channels (ASICs) are activated by extracellular protons and are involved in
neurotransmission in the central nervous system, in pain perception, as well as in …

Homomeric acid-sensing ion channel 1 (ASIC1) can be activated by extracellular H+ in the
physiological pH range and may, therefore, contribute to neurotransmission and peripheral …

Acid-sensing ion channels (ASICs) are Na+-permeable ion channels activated by protons
and predominantly expressed in the nervous system. ASICs act as pH sensors leading to …

Acid-sensing ion channels ASIC1a and ASIC1b are ligand-gated ion channels that are
activated by H+ in the physiological range of pH. The apparent affinity for H+ of ASIC1a and …

ASIC3 is an acid-sensing ion channel expressed in sensory neurons, where it participates in
acidic and inflammatory pain. In addition to the" classical" transient current, ASIC3 generates …

Proton receptors of the acid-sensing ion channel (ASIC) family are expressed in sensory
neurons and thus could play a critical role in the detection of noxious acidosis. To …

Acid-sensing ion channels (ASICs) are voltage-independent Na+ channels activated by
extracellular protons. ASIC1a is expressed in neurons in mammalian brain and is implicated …

Acid-sensing ion channels (ASICs) are ligand-gated cation channels activated by
extracellular protons. In periphery, they contribute to sensory transmission, including that of …

Acid-sensing ion channels (ASICs) are widely expressed proton-gated Na+ channels
playing a role in tissue acidosis and pain. A trimeric composition of ASICs has been …

Acid-sensing ion channels (ASICs) are H+-gated Na+ channels, which are present in most, if
not all, neurons. The typical ASIC current is transient and is elicited by a rapid drop in the …