Crystal structure of the β chain of a T cell antigen receptor
GA Bentley, G Boulot, K Karjalainen, RA Mariuzza - Science, 1995 - science.org
The crystal structure of the extracellular portion of the β chain of a murine T cell antigen
receptor (TCR), determined at a resolution of 1.7 angstroms, shows structural homology to …
receptor (TCR), determined at a resolution of 1.7 angstroms, shows structural homology to …
Crystal Structure of the Vα Domain of a T Cell Antigen Receptor
BA Fields, B Ober, EL Malchiodi, MI Lebedeva… - Science, 1995 - science.org
The crystal structure of the Vα domain of a T cell antigen receptor (TCR) was determined at a
resolution of 2.2 angstroms. This structure represents an immunoglobulin topology set …
resolution of 2.2 angstroms. This structure represents an immunoglobulin topology set …
Transmembrane helical interactions and the assembly of the T cell receptor complex
N Manolios, JS Bonifacino, RD Klausner - Science, 1990 - science.org
Studies of the subunit interactions of the multicomponent T cell antigen receptor (TCR)
revealed that specific pairs of chains have the ability to assemble after transfection into …
revealed that specific pairs of chains have the ability to assemble after transfection into …
Expression of T cell antigen receptor heterodimers in a lipid-linked form
AY Lin, B Devaux, A Green, C Sagerström, JF Elliott… - Science, 1990 - science.org
The interaction of the T cell receptor for antigen (TCR) with its antigen-major
histocompatibility complex ligand is difficult to study because both are cell surface multimers …
histocompatibility complex ligand is difficult to study because both are cell surface multimers …
Selection of amino acid sequences in the beta chain of the T cell antigen receptor
SM Hedrick, I Engel, DL McElligott, PJ Fink, ML Hsu… - Science, 1988 - science.org
The induction of an immune response in mammals is initiated by specifically reactive T
lymphocytes. The specificity of the reaction is mediated by a complex receptor, part of which …
lymphocytes. The specificity of the reaction is mediated by a complex receptor, part of which …
Molecular cloning of the zeta chain of the T cell antigen receptor
AM Weissman, M Baniyash, D Hou, LE Samelson… - Science, 1988 - science.org
The T cell antigen receptor is a multi-subunit receptor complex present on the surface of all
mature and many developing T cells. It consists of clonotypic heterodimers noncovalently …
mature and many developing T cells. It consists of clonotypic heterodimers noncovalently …
An αβ T cell receptor structure at 2.5 Å and its orientation in the TCR-MHC complex
The central event in the cellular immune response to invading microorganisms is the specific
recognition of foreign peptides bound to major histocompatibility complex (MHC) molecules …
recognition of foreign peptides bound to major histocompatibility complex (MHC) molecules …
The T cell receptor
P Marrack, J Kappler - Science, 1987 - science.org
The primary structure of T cell receptor proteins and genes is well understood.
Immunologists are now trying to understand the properties of these interesting molecules …
Immunologists are now trying to understand the properties of these interesting molecules …
Structurally divergent human T cell receptor γ proteins encoded by distinct Cγ genes
The human T cell receptor (TCR) γ polypeptide occurs in structurally distinct forms on certain
peripheral blood T lymphocytes. Complementary DNA clones representing the transcripts of …
peripheral blood T lymphocytes. Complementary DNA clones representing the transcripts of …
The structure of the T cell antigen receptor
GA Bentley, RA Mariuzza - Annual review of immunology, 1996 - annualreviews.org
▪ Abstract Recent crystallographic studies of T cell antigen receptor (TCR) fragments from
the α and β chains have now confirmed the expected structural similarity to corresponding …
the α and β chains have now confirmed the expected structural similarity to corresponding …