Treatment limitations and clinical outcomes in critically ill frail patients with and without COVID‐19 pneumonitis

A Subramaniam, R Tiruvoipati… - Journal of the …, 2023 - Wiley Online Library
Background The presence of treatment limitations in patients with frailty at intensive care unit
(ICU) admission is unknown. We aimed to evaluate the presence and predictors of treatment …

[HTML][HTML] Characteristics and outcomes of patients with frailty admitted to ICU with coronavirus disease 2019: an individual patient data meta-analysis

A Subramaniam, C Anstey, JR Curtis… - Critical Care …, 2022 - journals.lww.com
OBJECTIVES: Frailty is often used in clinical decision-making for patients with coronavirus
disease 2019, yet studies have found a variable influence of frailty on outcomes in those …

[HTML][HTML] Older age and frailty are associated with higher mortality but lower ICU admission with COVID-19

MK Andrew, J Godin, J LeBlanc, G Boivin… - Canadian Geriatrics …, 2022 - ncbi.nlm.nih.gov
Background We report characteristics and outcomes of adults admitted to Canadian
Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS) Network …

Frailty and mortality in hospitalized older adults with COVID-19: retrospective observational study

R De Smet, B Mellaerts, H Vandewinckele… - Journal of the American …, 2020 - Elsevier
Objectives To determine the association between frailty and short-term mortality in older
adults hospitalized for coronavirus disease 2019 (COVID-19). Design Retrospective single …

Predictors for development of critical illness amongst older adults with COVID-19: Beyond age to age-associated factors

JP Lim, KYH Low, NJJ Lin, CZQ Lim, SWX Ong… - Archives of gerontology …, 2021 - Elsevier
Introduction Older adults with COVID-19 have disproportionately higher rates of severe
disease and mortality. It is unclear whether this is attributable to age or attendant age …

Divergent: age, frailty, and atypical presentations of COVID-19 in hospitalized patients

PCE Poco, MJR Aliberti, MB Dias… - The Journals of …, 2021 - academic.oup.com
Background Although frailty has been associated with atypical manifestations of infections,
little is known about COVID-19 presentations in hospitalized frail patients. We aimed to …

[HTML][HTML] Impact of frailty on clinical outcomes in patients with and without COVID-19 pneumonitis admitted to intensive care units in Australia and New Zealand: a …

A Subramaniam, K Shekar, C Anstey, R Tiruvoipati… - Critical Care, 2022 - Springer
Background It is unclear if the impact of frailty on mortality differs between patients with viral
pneumonitis due to COVID-19 or other causes. We aimed to determine if a difference exists …

[HTML][HTML] premorbid frailty is a better prognostic indicator than age in oldest-old hospitalized with COVID-19

R Piers, W Janssens, K Cobbaert, I Pattyn… - Journal of the …, 2021 - ncbi.nlm.nih.gov
Older people have a higher susceptibility for coronavirus disease 2019 (COVID-19) and a
higher risk of developing severe COVID-19 symptoms and mortality. 1 Current studies …

[HTML][HTML] Association between Clinical Frailty Scale (CFS) and clinical presentation and outcomes in older inpatients with COVID-19

A Martí-Pastor, O Moreno-Perez, E Lobato-Martínez… - BMC geriatrics, 2023 - Springer
Background Frailty is a physiological condition characterized by a decreased reserve to
stressors. In patients with COVID-19, frailty is a risk factor for in-hospital mortality. The aim of …

[HTML][HTML] Clinical features, inpatient trajectories and frailty in older inpatients with COVID-19: a retrospective observational study

CN Osuafor, C Davidson, AJ Mackett, M Goujon… - Geriatrics, 2021 - mdpi.com
Introduction: We describe the clinical features and inpatient trajectories of older adults
hospitalized with COVID-19 and explore relationships with frailty. Methods: This …